Improved Lyophilization Results: Arctic Blast with Series 3 HT Evaporator
13 Dec 2016
Benefiting from a state-of-the-art -75°C condenser, the Series 3 HT Evaporator from Genevac sets a new benchmark for enhanced evaporation and lyophilization results.
Drying HPLC purification fractions, such as water and acetonitrile, is a routine yet essential task in many pharmaceutical laboratories. Typically labs require HPLC fractions to be dried to a powder form, such that samples can be accurately weighed, easily sub-sampled and re-dissolved. To provide a rapid, high-throughput alternative to freeze drying of such samples - Genevac developed its proprietary fast lyophilization (LyoSpeed™) methodology for use on their HT Series Evaporators. While the LyoSpeed™ has traditionally worked well for hydrophilic samples - difficulties may arise where the sample do not readily dissolve in only water.
The Series 3 HT Evaporator features an integral -75°C condenser as standard. Operating at higher power than any other commercially available condenser, users of LyoSpeed™ on Series 3 HT Evaporators have reported that a greater percentage of samples yield dry powders than they have previously been able to achieve.
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Series 3 HT Evaporator
GenevacThe all new Series 3 HT evaporator range from Genevac represents the ultimate in solvent removal technology. The latest touchscreen technology, new high performance vacuum pump, and a sleek ergonomic design makes optimising your evaporation processes effortless. High speed, High throughput evaporation Front opening for easy access. New intuitive touchscreen control system for ultimate ease of use Integral condenser meaning a smaller system footprint Rugged design with clean lines and a modern look All the features and functionality you expect from a Genevac HT evaporator including Dri-Pure anti-bumping, automatic end of run, HCl resistance, Inert Gas Purge, Lyospeed and EXALT controlled crystallisation Available in HT-6 and HT-12 format, Series 3 HT evaporators feature a new 6 place rotor which accepts all existing Genevac HT series holders. Sample formats include microtitre plates, tubes, vials, flasks and SampleGenie - unique flask and sample holder technology which enables large volume samples to be dried or concentrated directly into the small vial of your choice. Intuitive touchscreen controls enhances monitoring and review of the whole evaporation process. For popular solvent removal protocols pre-set 'Press & Go' methods makes operation easy and productive even for occasional users. Simplified manual and automatic programming means even the most complex multi-stage evaporation methods can be set-up and run quickly and easily. Genevac HT Evaporators are designed to provide the ideal solution for evaporation bottlenecks in the drug discovery laboratory. High performance and high sample capacities make them the ideal workhorses for the busy medicinal chemistry laboratory. Applications: High Throughput Chemistry and Parallel Synthesis LC/MS or HPLC Purification Fast Lyophilisation of purification fractions Natural Products Research Oligosynthesis Flash Chromatography Process Development.