Next-generation Orbitrap mass spectrometers deliver 4x faster results and 5x higher sensitivity across 300+ applications

We’re really focused on extending our Orbitrap HRAM technology. Obviously, the research market is something that we’re still very involved in and enabling the high end of research, but also pushing all the way down through post-research analytical development and even into the applied market. So we’re talking about multiomics, biopharma, small molecule, structural biology, and even into the environmental labs, environmental applications and workflows, so making sure that we’re keeping the water safe and clean, and all the way through to food applications where we’re keeping the food safe. With the Tribrid technology now used in over 300 different research applications, so very broad, and the new Orbitrap Tribrid Apex is being used in all of those applications, and it also delivers five times higher sensitivity, up to 100% sequence coverage, and results up to four times faster. So scientists can see more and get their results even quicker. So one of the releases that we’ve just made is the new Orbitrap Exploris GC S mass spectrometer, which is really focused on regulated dioxins and persistent organic pollutants in a full workflow. So it enables those scientists to see more and much faster.

We’re really excited to introduce the Thermo Scientific Orbitrap Tribrid Apex mass spectrometer. This innovation is really the most versatile Orbitrap that we’ve ever brought to the market. What makes it versatile is that it combines direct mass technology, which helps our customers analyze larger and more complex molecules, particularly biotherapeutics, identifying their charge state. But then we combined it with alternative fragmentation. We have a new IR laser. And what’s really powerful about this is it can be combined with other forms of alternative fragmentation and put together, including ETD and HCD. This creates a very data-rich environment, which then our AI-powered software improvements can extract more information for our customers faster than ever before. So the new innovation of the Orbitrap Tribrid Apex is really part of an end-to-end workflow solution that combines separation with our Vanquish Neo systems, like our new Vanquish Amplify. It’s a bioinert system designed for oligonucleotide analysis, and then our mass detector with the Orbitrap Tribrid Apex, and our new software solutions, which have really been enhanced by AI, such as BioPharma Finder and Compound Discoverer. And then we wrap this all together from a customer experience with our Unity Lab Services, which ensures our customers are successful from installation through daily operation. So we’ve also recently introduced the Thermo Scientific Orbitrap Excedion Mass Spectrometer. What makes this instrument really unique is that it has enhanced dynamic range. This helps our customers, particularly those in the pharmaceutical industry, see more of what’s in their sample. So when they want to analyze small molecules to understand how the body metabolizes them to ensure they’re creating safe and effective therapeutics, one of the most exciting advances is really in the field of proteomics, where we’re combining not just mass spectrometry-based proteomics with our Orbitrap Astral Zoom platform in particular, but how that is complementary to the OLink solutions, which really allows the power of precision medicine to be scalable across large cohorts. An example of that is the PRECISE study in Singapore, which is really being powered then on the back end by next-generation AI-driven data analytics. This will help create personalized medicines in the future.

The technology never stops. And we’re seeing the mass spec technology again continuing to grow at the high end of research, but also now some of those HRAM technologies push further down into the value chain, even all the way down through to some of the applied markets, food safety and water testing, environmental testing. And the other thing that’s really, I guess, a megatrend and something that we’re very involved in is building those AI and machine learning tools into the software to help scientists find what they’re looking for but make decisions faster.