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DynaPro ZetaStar: Automation, speed, and simplicity for nanoparticle characterization

18 Feb 2026
DynaPro ZetaStar: Automation, speed, and simplicity for nanoparticle characterization

In this video, Wyatt Technology demonstrates the power of automated nanoparticle characterization with the DynaPro™ ZetaStar™. Combining dynamic, electrophoretic, and static light scattering in one advanced system, it delivers precise measurements of size, polydispersity, zeta potential, particle concentration, molar mass, and turbidity, all in a single instrument. From viral vectors and lipid nanoparticles to proteins, polymers, and nucleic acids, the ZetaStar analyzes molecules ranging from angstroms to microns with speed and confidence.

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Waters | Wyatt Technology

Wyatt Technology, a business unit of Waters Corporation, is the world leader in light scattering instrumentation for characterizing macromolecules and nanoparticles in solution. Wyatt’s products determine absolute molar mass, size, charge, interaction properties, conformation and conjugation. The company offers a complete suite of multi-angle light scattering (MALS) instruments, field-flow fractionation (FFF) systems, dynamic light scattering (DLS) and zeta potential instruments and detectors to measure refractive index and intrinsic viscosity.

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DynaPro™ Zetastar™ Dynamic, Electrophoretic, and Static Light Scattering Detector

Waters | Wyatt Technology

Unique among its peers, the DynaPro™ Zetastar™ performs simultaneous dynamic and static light scattering or dynamic and electrophoretic light scattering (DLS/SLS/ELS) measurements all within one instrument. Measure manually with microcuvettes, or automatically via an autosampler and flow cell. Quickly assess size, polydispersity, zeta potential, charge, particle concentration, molar mass or turbidity for characterization and stability studies.

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Particle CharacterizationParticle characterization instruments are used to determine particle size distribution, shape, surface area, zeta potential, density and porosity of particles and materials. Multiple tecchniques are available for determining particle size, shape and count including dynamic light scattering (DLS), laser diffraction, electrozone (Coulter technique), imaging particle analysis and single particle optical sensing. Determine the density of your material with a gas pycnometer or examine its surface area and porosity with gas adsorption analyzers and mercury porosimeters. Find the best particle characterization instruments in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.