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Yarra 1.8μm SEC-X150 Columns - Superior Stability under Harsh Conditions

21 Jul 2016

This application note demonstrates the performance advantages of Yarra 1.8μm SEC-X150 Columns from Phenomenex for the analyses of biomolecules by aqueous size exclusion chromatography (SEC). The switching of mobile phases was used to simulate stress on the silica bed. Faster flow rates served to increase the backpressure to atypical levels and the stoppage of flow after each series of steps mimicked the completion of a series of samples. Column failure was not actually achieved after this study was completed, modeling the stable performance of Yarra SEC-X150 columns over longer lifetimes.

Yarra Ultra-High Efficiency Aqueous GFC/SEC Columns

Phenomenex Inc

Starting with 3 µm ultra-pure silica, Yarra particles are densely bonded with a proprietary surface chemistry. Coupled with tight particle and pore size distribution as well as strict packing and QC specifications, Yarra GFC columns allow for the highest efficiencies and resolution possible. Yarra columns are offered in three phases (SEC-2000, 3000, and 4000), and are ideal for the separation of small to large proteins, as well as biological therapeutics and biosimilars.

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