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Using UHPLC/MS (TOF) for Detection of Drugs and Metabolites in Urine following Optimized Enzymatic Hydrolysis Conditions

Using UHPLC/MS (TOF) for Detection of Drugs and Metabolites in Urine following Optimized Enzymatic Hydrolysis Conditions

18 Jan 2016

The goal of the study presented here was to determine optimal conditions for β-glucuronidase from various species toward hydrolysis of different compound classes with subsequent analysis by UHPLC/MS (TOF).

Titan™ C18 UHPLC Columns, 1.9 μm

Sigma-Aldrich Supelco

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