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Tizanidine HCl tablet with precision

23 Mar 2022

Tizanidine has several amine groups which can present problems to chromatographers. In this application note, MicroSolv Technology Corporation demonstrates how the Cogent Amide Column is virtually free of residual silanols and therefore a symmetrical peak shape can be obtained.

Cogent Amide Hydride™

MicroSolv Technology Corp.

Cogent Amide Hydride™ HPLC Columns are manufactured with TYPE-C™ silica (silica hydride) and have an ethyl amide functional group bonded to the silica particle with direct, silicone-carbon bonds.  The manufacturing of silica makes these columns extremely stable.    

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