Particle size analysis by DLS for optimization of protein complexes for measurement by small-angle neutron scattering

3 Feb 2025

Explore how dynamic light scattering (DLS) can be used to ensure monodispersity in protein samples for small-angle neutron scattering (SANS) studies. Discover how researchers using the DynaPro™ Plate Reader, detected protein aggregation that was undetectable by SDS-PAGE and UV spectroscopy. This method enhances sample quality assessment, ensuring reliable SANS measurements for studying Type I bacterial restriction-modification systems.

DynaPro™ Zetastar™ Dynamic, Electrophoretic, and Static Light Scattering Detector

Waters | Wyatt Technology

Unique among its peers, the DynaPro™ Zetastar™ performs simultaneous dynamic and static light scattering or dynamic and electrophoretic light scattering (DLS/SLS/ELS) measurements all within one instrument. Measure manually with microcuvettes, or automatically via an autosampler and flow cell. Quickly assess size, polydispersity, zeta potential, charge, particle concentration, molar mass or turbidity for characterization and stability studies.

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