Manual extraction of PFAS in drinking water in compliance with EPA Method 537.1

Per- and polyfluorinated alkyl substances (PFAS) have been used abundantly since their inception in the twentieth century and have become a closely monitored class of compounds within environmental testing. This application note outlines a procedure for those seeking to become compliant with EPA Method 537.1. The data presented was generated using a Biotage^® VacMaster™ vacuum manifold with a Large Volume Extraction (LVE) kit designed for PFAS work in conjunction with ISOLUTE^® 101 SPE columns and a TurboVap^® LV system. This note will demonstrate that the solution outlined is capable of generating data which exceeds the requirements outlined within the 537.1 method.