Introduction to Functionalized Silica Gel and Alumina RediSep® Columns
Introduction to Functionalized Silica Gel and Alumina RediSep® Columns
16 Jul 2015This application provides an introduction to Isco’s RediSep® Columns loaded with functionalized silica gel and basic, acidic, and neutral alumina. The use of neutral alumina can be helpful for separation of compounds without running the risk of acidity breaking down a compound and with an acid or base moiety covalently bound to the stationary phase, the need to switch solvents is eliminated.
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RediSep® Alumina Columns
Teledyne LabsNeutral alumina columns are useful when samples are acid sensitive and prone to degradation on normal phase silica gel. Acid and basic alumina columns are useful when purification of a compound with those properties is considered. This avoids the solvent swapping and additional extraction, washing, and concentration involved in recovering target compounds from collected fractions containing a mobile phase modifier such as triethylamine or acetic acid.