InertSep Oligo SPE

14 Oct 2025

Quantifying oligonucleotide therapeutics demands high sensitivity, selectivity, and reproducible sample prep, especially in LC/MS workflows where distinguishing parent compounds from metabolites is critical.

Discover how InertSep Oligo streamlines purification with automation-ready solid phase extraction (SPE) formats, delivering consistent recovery and minimal variability. Its LC/MS-compatible sorbent ensures reliable performance across scales, supporting high-throughput nucleic acid analysis with precision.

InertSep Oligo

GL Sciences, Inc.

InertSep Oligo is a solid-phase extraction (SPE) product for oligonucleotide purification in LC/MS workflows. It delivers high recovery, low variability, and full LC/MS compatibility. Formats include 96-well plates—Micro Elution (2 mg/400 µL) and 2 mL square-well (25 mg)—and straight barrel cartridges in multiple sizes for manual or automated high-throughput sample prep.

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InertSep Oligo SPE