Use case: His-tag protein expression screening from crude lysates

10 Nov 2025

His-tagged proteins underpin work across structural biology, assay development, and drug discovery. When screening many constructs, teams need quick, quantitative readouts from crude lysates to decide what to scale and what to drop.

In this application note, Abselion demonstrates how by using a His-tag assay on the Amperia™ platform, teams can obtain reproducible concentration measurements directly from unpurified samples, informing expression and purification decisions earlier.

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