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High-throughput and sensitive size exclusion chromatography (SEC) of biologics using Agilent AdvanceBio SEC Columns

15 Jul 2021

In this application note, Agilent Technologies demonstrates the use of shorter and narrower Agilent AdvanceBio SEC columns for fast, high-resolution, sensitive, and reproducible separation and quantitation of monoclonal antibodies (mABs) and antibody drug conjugate (ADC).

Agilent 1260 Infinity II Bio-Inert LC System

Agilent Technologies

The 1260 Infinity II Bio-Inert LC is a dedicated solution for analysis of large biomolecules in biological samples, including monoclonal antibody (mAb) and protein analysis. Metal-free components in the sample flow path and the absence of iron and steel in solvent delivery lines ensure the integrity of your biomolecules, minimize unwanted surface interactions, and increase column lifetime.

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AdvanceBio SEC

Agilent Technologies

Agilent AdvanceBio SEC columns ensure easy, fast, and accurate quantitation for mAb aggregation and fragment analysis. AdvanceBio SEC offers two different particle sizes, 2.7 and 1.9 µm.

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