High Sensitivity Measurement of Underivatized Estradiol by LC/MS/MS using Titan™ C18 Monodisperse Silica Columns
High Sensitivity Measurement of Underivatized Estradiol by LC/MS/MS using Titan™ C18 Monodisperse Silica Columns
19 Jan 2016The sex hormone estradiol is crucial for the development, maintenance, and regulation of female secondary sex characteristics. In postmenopausal women, loss of estrogen is a principal factor in the development of osteoporosis. For the measurement of estradiol in human serum, a fast and robust LC/MS/MS method was developed using Titan C18 UHPLC columns.
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Titan™ C18 UHPLC Columns, 1.9 μm
Sigma-Aldrich SupelcoTitan UHPLC columns, based on 1.9 µm totally porous monodisperse silica, outperform other UHPLC columns. These UHPLC columns provide the performance scientists expect (typically > 250,000 N/m), but at a greatly reduced cost. With the narrowest particle size distribution of all available sub-2 µm porous particles, Titan columns are the outcome of the highly efficient patent pending Ecoporous™ silica manufacturing process that delivers high-performance silica at a low cost. Read about how this product was used to analyze Riboflavin and impurities here and used in purification methods here. Features & Benefits: • Excellent Performance • Extremely Narrow Particle Size Distribution • Great Value