Formation of Spheroids and Suppression of Adhesion by Adherent Growing Cells in inertGrade™ Microplates
11 Nov 2016Suppression of the integrin mediated cell adhesion is vital in many experimental procedures, such as the production of embryonic bodies, self-assembled 3D cultures, and tumor spheroids. This application note describes a study in which BRANDplates® interGrade™ microplates where used to successfully suppress adhesion of a variety of adherent growing cell lines. The study also compares interGrade™ to competitor cell-repellent surfaces and found that when using interGrade™, larger numbers of smaller aggregates form and are uniformly distributed over the entire well surface when using.
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BRANDplates Cell Culture Microplates - inertGrade™
BRANDTECH® Scientific, Inc.BRANDplates® inertGrade™ 96-well plates are especially suited for cell culture applications when adhesion is not desired. These plates are specifically designed for the cultivation of suspension, tumor, and stem cells, as well as other spheroid or 3-dimensional tissue culture models. They feature a surface that reduces cell adhesion and protein absorption to minimize enzyme and cellular activation. All BRANDplates® inertGrade™ microplates are sterile according to Ph. Eur. and USP 29, SAL10-6, and are alphanumerically coded with orange embossing for easy plate and well identification. Available clear, white, and black, with U- F- or C-bottom, as well as white or black with transparent bottom, to suit your needs.