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Fluoxetine (Prozac)
23 Mar 2022Fluoxetine can have a tendency to tail in some HPLC methods due to its secondary amine group. In this application note, MicroSolv Technology Corporation demonstrates how peak shape with the Cogent Amide Column was found to be highly symmetrical without the aid of ion pairing agents. This allows the method conditions to be adapted to LC-MS if needed.
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Cogent Amide Hydride™
MicroSolv Technology Corp.Cogent Amide Hydride™ HPLC Columns are manufactured with TYPE-C™ silica (silica hydride) and have an ethyl amide functional group bonded to the silica particle with direct, silicone-carbon bonds. The manufacturing of silica makes these columns extremely stable.