Efficacy of Enhanced Confirmation Criteria to Reduce False Positive Detections in Forensic Screening

This application note describes a study demonstrating the use of liquid chromatography-quadrupole time of flight (LC-QTOF) mass spectrometry to screen urine and serum samples for compounds covering a wide variety of drug classes relevant to post-mortem and routine forensic drug screening. A database was created for the processing of the TOF MS full scan data of the 61 compounds detected.