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Direct Analysis of Red Wine Using Ultra-Fast Chromatography and High Resolution Mass Spectrometry

7 Apr 2014

This application note demonstrates the feasibility of analyzing complex mixtures without any prior sample preparation by making use of the high resolving power of both U-HPLC and the Orbitrap™ mass analyzer detector.

Thermo Scientific LTQ Orbitrap XL

Thermo Fisher Scientific

Thermo Scientific LTQ Orbitrap XL - The Most Confident Protein Identification The Thermo Scientific LTQ Orbitrap XL hybrid FTMS (Fourier Transform Mass Spectrometer) supports a wide range of applications from routine compound identification to the most challenging analysis of low level components in complex mixtures. The LTQ Orbitrap XL is based on the fast and highly sensitive Thermo Scientific LTQ XL linear ion trap and the patented Orbitrap* technology. The LTQ Orbitrap XL features a new HCD collision cell for ultimate flexibility in fragmentation experiments for advanced proteomics and small molecule research. Key features of the Thermo Orbitrap XL include: Outstanding Mass Accuracy, Resolution, Dynamic Range and Sensitivity • Featuring the new HCD collision cell for ultimate flexibility in fragmentation experiments for advanced proteomics and small molecule research • Superior mass accuracy for lower false positive rates (FPRs) • Parallel acquisition mode for optimized productivity From Protein ID to Biomarker Discovery with the Thermo LTQ Orbitrap• Excellent sensitivity and fragmentation efficiency • Reliable identification and quantitation in one experiment High quality data from the LTQ Orbitrap XL for reliable de novo sequencing • Superior mass accuracy and high resolution leading to confident de novo sequencing results • Multiple collision modes (CID and HCD) for comprehensive structural information

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Direct Analysis of Red Wine Using Ultra-Fast Chromatography and High Resolution Mass Spectrometry