Detection of sibutramine in slimming products by HPTLC and confirmation by HPTLC-MS

Diet foods, such as slimming coffee or dietary food supplements, are widely marketed and numerous preparations are available to consumers through several distribution channels. They are particularly easy to obtain via the internet. The fraudulent addition of sibutramine has recently been detected in many tainted natural slimming pills and is of serious health concern. In this application note, CAMAG demonstrates how the presence of sibutramine may be identified using thin-layer chromatography-mass spectrometry.