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Better Gel Filtration: A New Look at Method Development Parameters Using Yarra™ GFC Columns

12 Jan 2015

An affordable, high efficiency Yarra GFC column was recently introduced and is significantly more efficient than other GFC columns on the market. In addition to higher efficiency, Yarra columns demonstrate significantly higher inertness to ionic interactions versus other GFC columns; however, such chemical characteristics require optimization to operating parameters. Performing method development through mobile phase composition using next-generation Yarra GFC columns will be discussed.

Yarra Ultra-High Efficiency Aqueous GFC/SEC Columns

Phenomenex Inc

Starting with 3 µm ultra-pure silica, Yarra particles are densely bonded with a proprietary surface chemistry. Coupled with tight particle and pore size distribution as well as strict packing and QC specifications, Yarra GFC columns allow for the highest efficiencies and resolution possible. Yarra columns are offered in three phases (SEC-2000, 3000, and 4000), and are ideal for the separation of small to large proteins, as well as biological therapeutics and biosimilars.

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Better Gel Filtration: A New Look at Method Development Parameters Using Yarra™ GFC Columns