ResourceLife Sciences
Assessing reader capability for NanoBRET technology
11 Mar 2025This application note demonstrates the performance of NanoBRET™ technology for detecting protein interactions in living cells, using SpectraMax® Multi-Mode Microplate Readers. By leveraging the high sensitivity and flexible detection options of these instruments, researchers can accurately measure NanoBRET signals and analyze data with SoftMax® Pro Software. The note highlights assay validation across five reader models, showcasing their capability to deliver reliable results with enhanced signal quality and low background.
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Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.BRET

