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Anion-exchange chromatography for determining empty and full capsid contents in adeno-associated virus

29 May 2022

This application note demonstrates how AAV8 empty and full capsids can be separated, and their relative abundances determined using a Waters Protein-Pak Hi Res Q Column.

ACQUITY UPLC H-Class PLUS Bio System

Waters

The ACQUITY UPLC H-Class PLUS Bio System delivers the benefits of UPLC's resolution, sensitivity, and throughput in a system purpose-built for the analysis of proteins, peptides, nucleic acids, and glycans.

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