Protein Crystallography Products & Reviews

Automated membrane protein screening, optimization, and scale-up to empower better protein crystallization research. 

mosquito crystal helps scientists to automate and streamline liquid handling workflows in protein crystallography drop setting and beyond while enhancing research quality and productivity. 

mosquito Xtal3 delivers protein crystallization without compromise. 

Trypsin/Lys-C Mix, Mass Spec Grade, is a mixture of Trypsin Gold, Mass Spectrometry Grade, and rLys-C, Mass Spec Grade. The Trypsin/Lys-C Mix is designed to improve digestion of proteins or protein mixtures in solution.   Using the conventional trypsin digestion protocol (i.e., overnight incubation at nondenaturing conditions), Trypsin/Lys-C Mix improves protein digestion by eliminating the majority of missed cleavages,…

Trypsin is a serine protease that specifically cleaves at the carboxylic side of lysine and arginine residues.   The stringent specificity of trypsin is essential for protein identification. Native trypsin is subject to autolysis, generating pseudotrypsin, which exhibits a broadened specificity including a chymotrypsin-like activity. Such autolysis products, present in a trypsin preparation, would result in addition…

Reliable Drop Setting: Reduce Costs + Increase Reproducibility The NT8 ® - Drop Setter/Crystallization Robot is a fast, nanoliter-volume liquid handler with drop dispensing capability, including setting drops for Lipidic Cubic Phase (LCP) experiments. The 8-tip head aspirates and dispenses drops from 10 nL to 1.5 μL.

Build Crystallization Screens with Ease The FORMULATOR ® - Screen Builder is a next-generation liquid handler specifically designed for Protein Crystallography that uses patented microfluidic technology to dispense up to 34 different ingredients to design even the most complex optimization screens. A 96-nozzle dispensing chip can dispense any volume of any ingredient of any viscosity into any well.

The PCT Pre-Crystallization Test is used to determine the appropriate protein concentration for crystallization screening. Sample concentration is a significant crystallization variable. Samples too concentrated can result in amorphous precipitate, while samples too dilute can result in clear drops. Precipitate and clear drops are typical crystallization screen results for reagent conditions which do not promote crystallizati…

Grid Screen Salt HT combines Grid Screen Ammonium Sulfate, Grid Screen Sodium Malonate, Quik Screen and Grid Screen Sodium Chloride into a single 96 Deep Well block format. The block contains 1 ml of each reagent. Features: A systematic grid screen varying salt or polymer or organic versus pH Samples pH 4 to 9 Combine reagents within or between screens to customize your screen Combine reagents between rows or colum…

Upgrade your crystallization screens with the New Industry Standard: The Crystal16 benchtop crystallization system.

The Crystal Phoenix is the ideal protein crystallography dispenser, featuring accuracy, speed and precision to make it the perfect instrument for sitting drop, hanging drop and microbatch reactions. In less than 50 seconds it dispenses protein and screen to the small wells or hanging drop seals. The speed of dispensing the screen and protein eliminates the problem of evaporation even when dispensing as little as 100 nanolite…

Harnessing innovative positive displacement pipetting to simplify protein crystal optimization 

Remove the guesswork. SONICC ® finds protein crystals that other technologies cannot. The ultimate imaging technology in visualizing protein crystals, Second Order Nonlinear Imaging of Chiral Crystals (SONICC) definitively finds crystals buried in precipitate or submicron crystals naked to the eye. 

Crystal Clear Imaging. Unparalleled Speed. ROCK IMAGER ® - Crystallization Imagers are a series of automated imaging systems designed for protein crystallization screening. Capture superior quality images of your protein drops while learning critical information about your crystals. ROCK IMAGERs are available with various plate capacities and imaging features, so there is a model to fit every lab's budget and workflow.

The Crystal Screen and Crystal Screen 2 reagent kits are designed to provide a highly effective and rapid screening method for the crystallization of macromolecules. The screens are simple and practical for finding initial crystallization conditions. The initial crystallization conditions for more than 1,000 proteins, peptides, oligonucleotides, and small molecules have been determined using Crystal Screen.A highly effective…

Originally published in 1991 by Jancarik & Kim from conditions found to be successful in the crystallization of biological macromolecules. This classic standard sparse matrix screen lets you: Determine initial crystallization conditions. Establish the solubility of a macromolecule in a varying range of pH and precipitants. and with the enhanced buffer selection enables screening of greater crystallization space.Structure Scre…

PEG/Ion, developed by Hampton Research, is a crystallization screen designed to evaluate monodisperse, high purity Polyethylene glycol 3,350 and 48 unique salts representing a very complete range of anions and cations frequently used in the crystallization of biological macromolecules. The primary screening variables are PEG, ion type, ionic strength, and pH. More than 60% of the published crystallizations utilized PEG as a p…

SaltRx was developed by Hampton Research as a primary and secondary, salt and pH based crystallization screen for biological macromolecules. Salt is the only primary crystallization reagent (precipitant) utilized. Based on a design of 96 conditions, the screen evaluates a broad portfolio of crystallization salts of varying concentration and pH.SaltRx can be used as a primary crystallization screen when salt, ionic strength an…

Index is designed as a 96 reagent crystallization screen that combines the strategies of the grid, sparse matrix, and incomplete factorial screening with traditional, contemporary, and new crystallization reagent systems into a highly effective and efficient format. Index, as the name implies, efficiently samples a series of specially formulated reagent zones to identify which reagent class or classes and pH are effective in…

Individual reagents from the Grid Screen Ammonium Sulfate and Grid Screen Salt HT screens. Grid Screen Ammonium Sulfate Individual Reagents Features: 185 ml volume Sterile filtered Applications: Individual Grid Screen Ammonium Sulfate and Grid Screen Salt HT screen reagents for screening, optimization and production

Automated Multipurpose Powder X-Ray Diffractometer

The HRP is purified by repeated affinity chromatography of root extracts from horseradish. The result is an enzyme of high specific activity. Our horseradish peroxidase is purified in large scale by the use of benzhydroxamic acid agarose giving a product of high purity and specific activity. The product consists mainly of the basic isoenzymes and are supplied as lyophilized powder. Activity: >250 U/mg (25°C, Guaiacol as hydr…

CAS SciFinder -  The First Choice With SciFinder from CAS, you can increase your productivity and achieve faster breakthroughs Advancing the pace of research, Chemical Abstracts SciFinder search allows you to get results fast without compromising precision and accuracy. CAS SciFinder allows you to explore a wealth of information using sophisticated search and analysis technology. Chemical Abstracts SciFinder is a research d…

SAXSpace is a new nanostructure analyzer for small- and wide-angle X-ray scattering (SWAXS) studies of nanostructured materials. With its easy handling and push-button alignment, SAXSpace is ideally suited for routine SWAXS analysis and quality control applications. SAXS experts benefit from the spacious sample chamber and versatile sample stages, allowing for full experimental flexibility. This makes SAXSpace an ideal tool fo…

The Freedom EVO Protein Crystallography workstation is a highly flexible, fully scalable liquid handling platform that can be configured for semi- or complete automation protein crystallography experiments.