Crystal16
Upgrade your crystallization screens with the New Industry Standard: The Crystal16 benchtop crystallization system.
Temperature dependent solubility curves in only 4hr
The supplier does not provide quotations for this product through SelectScience. You can search for similar products in our Product Directory.
Crystal16 is very good and would recommend buying for those working in a similar area.
Crystallization studies like MSZW, clear and cloud point detection, polymorph, solvates and salt
Purchasing and delivery process was very smooth. Instrument was installed by Technobis technician, training was detailed and good. Instrument is very robust. I've never faced any issues. Even for small doubts, Technobis' team reply very quickly and in depth. Overall after sales service is also good.
Review Date: 26 Jun 2020 | Technobis Crystallization Systems
Easy to use and really qualitative data!
Determination of solubility curves
The Crystal16 is an indispensable tool for a crystallization laboratory. For basic applications, it is really easy to use and solubility curve determination is made really easy and fully automated. In addition, the software for data processing is really well made and user-friendly. Some minor faults though: the hook hastelloy stirring system is not working when the caps of the vials are tightened (but the classic system with stirring bars works perfectly well) and it is not easy to use it at rather low temperatures (below 2°C approximately). Nevertheless, I would highly recommend this device for anyone needing to determine solubility curves or conduct crystallization experiments. In my lab, we even used it to conduct cooling crystallization experiments.
Review Date: 19 Jun 2020 | Technobis Crystallization Systems
Expedited solubility curve development.
Solubility curve development
It has been very efficient at what it was marketed to us for - solubility curve development. We're pleased with the support we've received for the US sales person.
Review Date: 19 Jun 2020 | Technobis Crystallization Systems
Mandatory for any physical chemistry or solid state lab!
Build solubility curves for pharmaceutical compounds and perform crystal growth
Device is easy to handle and relevant for getting solubility curves and the metastable zone in some cases. The software is very friendly and the device quite robust. Extremely slow cooling/heating rates (0.01°C/min) can be achieved and an experiment can run for days and days without any issues. Results are reproducible. CrystalClear is also good software for treating data and drawing solubility curves (or you can just export the raw data). There are many accessories for stirring or you can simply use a magnetic stirrer. Dried air is enough to go below 0°C. I worked with one with the cameras on each vial years ago. Very interesting to observe the nucleation and crystal growth.
Review Date: 18 Jun 2020 | Technobis Crystallization Systems
Applications:
- Solubility & MSZW determination
- Solvents selection
- Solubility mapping
- Phase diagrams
- Polymorphs, salts and cocrystals
- Amorphous solid dispersions
Brochures
Introducing the Crystal16 multi-reactor benchtop system
This product brochure describes the features of the Crystal16 multi-reactor benchtop system. The Crystal16 is designed with simple, user-friendly, and flexible software to perform medium-throughput crystallization studies at 1 mL scale.
Co-crystal screening: From smart design to effective experimentation
In this case study, Technobis Crystallization Systems details the use of two cutting-edge developments in the field of co-crystal screening. Download to explore the full process of how a febuxostat p-toluenesulfonic acid co-crystal was first predicted using a cutting-edge machine learning algorithm, and then subsequently obtained experimentally using the Crystal16 device.
Screening for co-crystals with a solubility-based approach
In this application note, Technobis discusses the use of the Crystal16 instrument as a tool for co-crystal screening. Within the pharma industry, active ingredients are commonly formulated as solid dosages, however the properties of the solid form of the actives are not always ideal. Therefore, crystal engineering is often employed to improve properties.
Automate your crystallization experiments using the CrystalBreeder and Crystal16
The CrystalBreeder and Crystal16 are useful tools to perform automated and controlled solid-state screens. This application note highlights ways in which these instruments can improve and accelerate crystallization research without compromising on flexibility.
Improving solubility: Stabilizing the amorphous state using the Crystal 16
The Crystal16 offers an invaluable tool to automate the execution of amorphous solid dispersion screening technology to quickly and effectively identify new solid dispersions of compounds. This application note provides ways in which the Crystal16 can be used in polymer applications.
Solubility: Importance, measurements and applications
This application note covers two dynamic methods for effective and reproducible solubility data generation: the temperature variation and solvent addition methods. These methods can be easily applied by making use of the turbidity probes integrated in the Crystal16 and particle viewer cameras of the Crystalline instruments.
The new industry standard Crystal 16: Designed by scientists for scientists
This video introduces the Crystal16 multi-reactor benchtop system. The Crystal16 is designed with simple, user-friendly, and flexible software to perform medium-throughput crystallization studies at 1 mL scale.
Technobis Crystallization Systems
Technobis Crystallization Systems is a technology provider for solid-state research, process development and formulation who's mission is to help research succeed!
Technobis' three systems:
The CrystalBreeder® is the first crystallizer dedicated for both development and discovery, carrying out complete crystallization screens with as little as 1mg of sample.
The Crystal16® parallel crystallizer is a multiple reactor station providing a screening solution for solubility determination, solid-state research and process development: medium-throughput crystallization studies at a 1ml scale.
With 8 independently controlled reactors and additional analytical capabilities, the Crystalline® is a unique modular product line at a working volume of 5 ml for solid-state research, process development and formulation research.
Conduct more crystallization studies with less research material
Technobis Crystallization Systems launches new modules for benchtop crystallization platform to boost its experimental capabilities
Tiny crystals, big data
New modules for Technobis’s crystallization platform enable scientists to perform vapor diffusion and evaporation crystallization screening
Enhancing efficiency with the new Crystal16
Technobis launches latest model of benchtop product with enhanced analytical capability
