Products & Reviews

Twist Oligo Pools are highly diverse collections of single-stranded oligonucleotides synthesized using our silicon-based DNA writing technology. Our synthesis platform enables massively parallel production of hundreds of thousands of high-quality, accurate oligos per run.

Twist Bioscience Gene Fragments improve your cloning process by minimizing colony screening. This allows you to save time and money by dramatically reducing cloning and sequencing costs. Think bigger, design on a grander scale, and accelerate your discoveries.

Unleash the full power of a well-designed library. With Twist Bioscience, you are assured that the library you design contains the specific modifications, exactly where you want them, saving you valuable resources for the downstream screening process.

Twist Custom Panels allow customers to create a customized NGS target enrichment panel that targets their specific regions of interest. Available for DNA, RNA, and methylation workflows, our bioinformatics team will help you design a panel tailored to your needs - created with the same double-stranded biotinylated probes that enable the exceptional performance of our fixed panels.

Twist Bioscience, the leader in synthetic DNA with unparalleled precision at scale, is redefining targeted sequencing performance with the Twist Human Core Exome Kit. This kit includes library preparation and enrichment components, allowing the flexibility to lower sequencing costs, increase sample throughput, and achieve a higher depth of coverage across target regions with uncompromising quality.

The Twist Human Comprehensive Exome Panel offers over 99% coverage of protein-coding genes, providing a solution for exome sequencing with high performance and flexibility.

Positive controls provide quality control measures for the verification and validation for point-of-care diagnostic tests including both next-generation sequencing (NGS) and reverse transcriptase-polymerase chain reaction (RT-PCR) assays. Twist offers fully synthetic SARS-CoV-2 RNA controls, available for dozens of distinct reference sequences.

The mouse is an extremely important model system for studying genetic variation, tumor mutations, and phenotypic outcomes as well as the therapeutic effect of pharmaceutical agents. As genetic variant databases are continuously updated, the Twist Mouse Exome panel is thoughtfully designed and built from the most current databases

The Twist Comprehensive Viral Research Panel covers reference sequences for 3,153 viruses, including 15,488 different strains.

Twist Library Preparation Enzymatic Fragmentation (EF) Kit 2.0 is built to help you achieve a more efficient sequencing pipeline and obtain more accurate Next-Generation Sequencing (NGS) results. This updated kit has new fragmentation and ligation modules, and includes the Equinox Library Prep Amp Mix. This hot-start enzyme formulation has a lower error rate* and high efficiency at low input volumes—making it ideal for samples…

High Throughput Antibody Production by Twist is a gene-to-protein workflow that relieves the costly bottleneck in discovery pipelines by producing tens to thousands of diverse antibodies for screening biophysical and pharmacokinetic properties. You submit the antibody sequence, and we’ll do the rest.

~4x more coverage of all CpG sites

Volume Verified Pipetting (VVP) delivers real-time volumetric verification for every channel, detecting air-in-sample events, clots, and clogs. With MEMS flow sensors and precise vacuum/pressure control, VVP ensures unmatched accuracy, reproducibility, and confidence in every liquid handling step.

The Lynx Robotic Liquid Handler—available in LM1800, LM1200, LM900, LM730i, and LM700 models—features Standard Technology (ST) pipetting tools, rapid on-the-fly tool swapping, and award-winning Volume-Verified Pipetting (VVP). With linear-motor motion and flexible deck designs, it delivers unmatched precision, throughput, and workflow integration.

Fully Automatable - Magnetic beads to clear lysate, avoiding manual centrifugation step Versatile - Process up to 1.5 mL bacterial cultures with different plasmid types and culture medias High-quality - Endotoxin-free plasmid DNA with endotoxin levels < 0.1 EU/µg Pure - Contamination-free plasmid DNA with A260/A280 > 1.8 and A260/A230 > 1.8

Recover DNA fragments from agarose gels in 15 minutes

Isolate gDNA from cultured cells, buccal swabs, whole blood and soft tissue using spin columns.

Isolates RNA from small samples with lower elution volumes using spin columns

Isolates RNA from whole blood using spin columns

The EXP® Hand-Tight Nut & Titanium Hybrid Ferrule fitting system is the premier adjustable nut and ferrule compression fitting for extreme high-pressure connections between 1/16" tubing and any 10-32 port. The patent-pending Titanium Hybrid Ferrule integrates the resilience of titanium with the proven sealing ability of PEEK in a superb one-piece design. The Hybrid Ferrule provides a perfect seal with every connection, yet the…

The EXP® Pre-Column Filter is ideal for protecting small-particle UHPLC columns at extreme pressures. Such techniques analyze samples in the most demanding applications, which can decrease the life of these expensive columns. EXP® Pre-Column Filters help extend that life and protect your column investment without sacrificing performance. Free-Turn® architecture allows the user to change cartridges by hand without breaking flui…

The cartridge-based EXP® Analytical Column System is designed for superior chromatographic analysis with each injection rated for routine use up to 20,000 psi.The new EXP® Analytical Column Holders incorporate Free-Turn® architecture allowing the user to quickly exchange columns, by hand, without breaking any fluid connections. The EXP® Analytical Column Holders are available in two formats: In-Line and Direct Connect, allowin…

OPTI-GUARD® 1mm Guard Columns set the standard for extremely low impact, easy to use pre-column protection. Designed for use with analytical (4.6, 3.0 mm i.d.) and narrow-bore (2.1, 1.0 mm i.d.) columns, the patented floating stem design automatically adjusts to any manufacturer's tube stop depth for a zero-dead-volume connection every time. The best part? It's no larger than a standard fitting. Connecting the OPTI-GUARD® requ…

The OPTI-PAK Trap Columns unique hardware design integrates a PEEK holder with an auto-adjusting stem which provides a fluid interface with any 10-32 standard injector port, and guarantees a zero-dead-volume connection despite variances in tube stop depth. A proprietary method of frit placement allows the packed stem to be positioned directly into the flow path, which eliminates all excess swept volume. Less swept volume trans…

Optimize Technologies, precision machine their components to the most exacting standards in the industry. Everything in the manufacturing process is controlled to ensure the continuing quality that has long been associated with the Optimize name. From the individual matching of check valve ball and seat sets to the proprietary blend of materials in our seals - experience the Optimize advantage.Most instrument manufacturers wil…