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ioSkeletal Myocytes Human iPSC-derived skeletal myocytes

bit.bio

Introducing highly-defined, consistent, and reliable human muscle cells for research, disease modeling, and high throughput screening across areas such as muscle, neuromuscular, and associated metabolic disorders. ioSkeletal Myocytes, part of the bit.bio ioCells portfolio, have been reprogrammed from human induced pluripotent stem cells (iPSCs) using bit.bio's precise reprogramming technology: opti-ox™  

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ioGlutamatergic Neurons Huntington's Disease HTT 50CAG/WT Human iPSC-derived glutamatergic neurons

bit.bio

A highly defined, scalable, and consistent source of human central nervous system (CNS) neurons carrying the disease-relevant 50 CAG trinucleotide repeat expansion associated with Huntington’s disease.  ioGlutamatergic Neurons HTT 50CAG/WT have been reprogrammed from human-induced pluripotent stem cells (iPSCs) using bit.bio’s precise reprogramming technology: opti-ox™ (optimized inducible overexpression).

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ioMicroglia Human iPSC-derived microglia

bit.bio

ioMicroglia are human induced pluripotent stem cell (iPSC)-derived microglia, precision reprogrammed using opti-oxâ„¢ technology. Within 10 days post-revival, ioMicroglia are ready for experimentation, expressing (>90%) key markers, including TMEM119, P2RY12, and IBA1. ioMicroglia display key functional traits including phagocytosis and proinflammatory cytokine secretion and can be co-cultured with ioGlutamatergic Neuronsâ„¢.

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Pharmacokinetics Assays

Prolytix

Pharmacokinetics (PK) is a crucial part of biopharmaceutical toxicology that evaluates the absorption, distribution, metabolism, and excretion (ADME) of biotherapeutics. Prolytix offers robust PK assays to support preclinical and clinical phases of biotherapeutic development.

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GMP Release Testing

Prolytix

GMP release testing is a critical quality control process that ensures manufactured therapeutics meet predetermined specifications before release. Prolytix provides GMP release testing for clinical and commercial drug substances and drug products.

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GMP Stability Testing & Storage

Prolytix

GMP stability testing determines how a drug product performs under routine and stressed conditions. Prolytix performs GMP‑compliant stability testing and provides ICH‑compliant storage to support clinical and commercial drug products.

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FP7000 Spectral Cell Sorter

Sony Biotechnology

The FP7000 is a high-parameter spectral cell sorter configurable with up to 6 lasers and 182 detectors that combines the versatile workflows from Sony's cell sorter portfolio with Sony's patented spectral technology to enable 6-way sorting and detection of more than 44 fluorescent parameters.

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Critical Reagent Manufacturing

Prolytix

Prolytix manufactures critical reagents under an ISO 9001‑certified quality system to support bioanalytical and GMP release testing, providing greater control and confidence in assay performance.

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Process Development

Prolytix

Process development services support the isolation, purification, and optimisation of large‑molecule drug manufacturing processes. Prolytix provides consultative process development to support efficient biologic development

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Biomarker Assays

Prolytix

Biomarker assays are laboratory methods that detect or analyse genes, proteins, or other molecules in biological samples and are fundamental tests in biotherapeutic drug monitoring, research, and development. Prolytix offers comprehensive biomarker assay development, validation, and testing services.

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