Cell Adhesion Assays Products & Reviews

The iLite® Fc Effector Reporter Gene Bioassays Portfolio offers a variety of reporter gene cell lines and target cells that can be used in MOA-reflective assays to measure the Fc effect of antibodies and other biologics that specifically bind and activate Fc receptors. Using a Luciferase reporter gene system offers a convenient and powerful way of measuring antibodies' in vitro efficacy in triggering ADCC and ADCP.

Svar offers assistance in gene therapy projects through robust platforms suited for all phases of drug development and experience from immunoassasy product development as well as their CRO services. Svar currently offer cell-based assays for Neutralizing antibody assessment and custom-made immunoassays for Total antibody assessment.

Complement biomarker assays target selected biomarkers of high relevance. These assays are important and well-suited for analyses in drug development and academic research. They stand out with very low cross-reactivity and high specificity as they bind neo-epitopes of cleaved products or complexes, where this is relevant.

In diagnosis of Rheumatoid Arthritis (RA), the measurement of anti-CCP is integral. People who test positive for Anti-CCP, are very likely to develop or have already developed RA, but not all who have RA, necessarily develop anti-CCP. Early detection of RA is crucial for reducing tissue damage.

Svar CRO Services provides direct value through an extensive toolbox of in-house products, scientific expertise, and end-to-end customizable solutions – everything to ensure the success of your drug development program.​

The Wieslab® Complement System Classical Pathway kit, available as IVD* and RUO, is a high-precision assay for detecting alternative complement pathway activity in human serum, the RUO is also suitable for primates and porcine samples. It uses ELISA technology with specific detection of C5b-9 for accurate results, offering advantages over traditional assays. *Subject to local registration.

The Wieslab® Complement System MBL Pathway kit, available as IVD* and RUO, is a high-precision assay for detecting alternative complement pathway activity in human serum, the RUO is also suitable for primates and porcine samples. It uses ELISA technology with specific detection of C5b-9 for accurate results, offering advantages over traditional assays. *Subject to local registration.

Wieslab® Complement Screen kit is available as both IVD* and RUO, detects Classical, MBL, and Alternative pathways in human serum samples using ELISA technology with specific detection of C5b-9 for accurate results offering advantages over traditional assays. The RUO is also suitable for primates and porcine samples. It is effective in complement therapeutics evaluation and drug development. *Subject to local registration.

The Factor P Functional assay is an ELISA that combines principles of the functional complement activity assays with the use of labeled antibodies specific for deposited complement proteins. The amount of deposited complement proteins is proportional to the functional activity of Properdin in the sample.

The iLite® CDC bioassay is based on a reporter gene and offers a convenient and powerful way of measuring antibodies' efficacy in eliciting complement-dependent cytotoxicity in test samples, including human serum.

RASTRUM™ is a 3D cell culture platform that enables scientists to generate biologically and phenotypically relevant models for disease research, drug discovery, and translational applications with greater efficiency and consistency.

For quantitative detection of human Laminin in cell culture supernates, serum and plasma(heparin, EDTA).

For quantitative detection of human VCAM-1 in cell culture supernates, serum and plasma(heparin, EDTA).

For quantitative detection of human soluble E-Selectin in cell culture supernates, serum and plasma(heparin, citrate).

For quantitative detection of human MFGE8 in cell culture supernates, serum, plasma(heparin, EDTA), saliva, urine and human milk.

For quantitative detection of rat Laminin in cell culture supernates, serum and plasma(heparin, EDTA).

Target Deconvolution service based on proteome-wide Cellular Thermal Shift Assay using Mass Spectrometry detection is performed in intact cells and lysate without any compound modifications.

Hit confirmation service is based on the Cellular Thermal Shift Assay (CETSA) and  allows for assessment of compound binding to a selected target protein in its native state without any modifications to the protein or the compound. 

Primary screening based on Cellular Thermal Shift Assay (CETSA) allows for rapid identification of high quality chemical starting points against the native, full-length protein in live cells. 

The CHEMICON® Alpha Integrin-Mediated Cell Adhesion Array kit is designed as a cost effective, efficient method for identification of cell surface integrins. The kit format uses 12 x 8-well removable strips in a plate frame for convenience and flexibility in designing assays. The Integrin-Mediated Cell Adhesion Array can be completed within 1-2 hours, providing a rapid, quantitative assay for the characterization of alpha inte…

The CHEMICON® Beta Integrin-Mediated Cell Adhesion Array kit is designed as a cost effective, efficient method for identification of cell surface integrins. The kit format uses 12 x 8-well removable strips in a plate frame for convenience and flexibility in designing assays. The Integrin-Mediated Cell Adhesion Array can be completed within 1-2 hours, providing a rapid, quantitative assay for the characterization of beta integr…

The CHEMICON® Alpha/Beta Integrin-Mediated Cell Adhesion Array kit is designed as a cost effective, efficient method for identification of cell surface integrins. The kit format uses 12 x 8-well removable strips in a plate frame for convenience and flexibility in designing assays. The Integrin-Mediated Cell Adhesion Array can be completed within 1-2 hours, providing a rapid, quantitative assay for the characterization of alpha…

The CHEMICON® Alpha/Beta Integrin-Mediated Cell Adhesion Array Combo Kit is designed as a cost effective, efficient method for identification of cell surface integrins. The kit format uses 12 x 8-well removable strips in a plate frame for convenience and flexibility in designing assays. The Alpha/Beta Integrin-Mediated Cell Adhesion Arrays can be completed within 1-2 hours, providing a rapid, sensitive, and quantitative assay…

The CHEMICON® ECM Cell Adhesion Array Kit (Colorimetric) provides an ECM Array microtiter plate with a colorimetric detection format, allowing for large-scale screening and quantitative comparison of multiple samples/cell lines. The kit is designed as a rapid (1-2 hours), cost effective, efficient method for characterization of cell adhesion.

The CHEMICON® ECM Cell Adhesion Array Kit (Fluorometric) provides an ECM Array microtiter plate with a homogenous fluorescence detection format, allowing for large-scale screening and quantitative comparison of multiple samples/cell lines. The kit is designed as a rapid (1-2 hours), cost effective, efficient method for characterization of cell adhesion