ADME-Toxicology Products & Reviews

A far-red viability dye staining nuclei in dead / apoptotic cells.

Apoptosis is a normal physiologic process which occurs during embryonic development as well as in maintenence of tissue homeostasis. The apoptotic program is characterized by certain morphologic features, including loss of plasma membrane asymmetry and attachment, condensation of the cytoplasm and nucleus, and internucleosomal cleavage of DNA. Loss of plasma membrane is one of the earliest features. In apoptotic cells, the mem…

This product is used for labeling of cells to trace multiple generations by flow cytometry.

This product is used for labeling of cells to trace multiple generations by flow cytometry.

Resolian has established itself as a world-class leader in biopharmaceutical drug development through analytical excellence with over 500 scientists across three global labs.

Vivid® CYP450 Screening Kits are high-throughput fluorescence-based assays for detection of enzyme-drug interactions and CYP450 inhibition. They provide an optimized method for studying isozyme-specific CYP450-drug interactions, metabolism, and inhibition. Vivid® CYP450 Screening Kits offer: Easy three-step procedure, "mix and read" format, reactions at room temperature or 37°C. Superior fluorescent properties and k…

Ready-to-use, dropper bottle far-red viability probe

Cell viability and vitality kit to measure metabolic activity and dead/non-viable nucleated cells.

Sensitive two-color fluorescence cell viability assay optimized for FITC and Texas Red filters

High-affinity DNA stain for studying cell viability and cytotoxicity

Sufficient for 100 colorimetric or fluorometric tests

The LIVE/DEAD Fixable Near-IR Dead Cell Stain Kit provides the stable components to determine the viability of cells prior to the fixation and permeabilization required for intracellular antibody staining or prior to elimination of biohazardous materials using formaldehyde fixation. The amine-reactive LIVE/DEAD Fixable Near-IR Dead Stain is an amine reactive dye that binds covalently to intracellular and extracellular amines i…

This assay kit provides an easy-to-use, non-radioactive, histological and FACS-based method for measuring cell proliferation, cell viability, chemotaxis, cytotoxicity and apoptosis. The kit provides a two-color fluorescence method that is based on the simultaneous determination of live and dead cells using two different dyes.  Live cells and intracellular esterase hydrolyzes the dye to produce a hydrophilic, strongly fluore…

BioLegend's FITC Annexin V Apoptosis Detection Kit with 7-AAD has been specifically designed for the identification of apoptotic and necrotic cells.

The HoloMonitor ® live cell imaging system enables long-term non-invasive analysis of cell cultures within your standard incubator. Cell biologists worldwide use PHI’s label-free cell imager to automatically obtain accurate live-cell morphology, migration, and proliferation data as well as multi-well time-lapse videos, down to a single-cell level in real-time.

Get faster staining and more accurate results - without the need for wash steps or quencher dye

Allows sensitive colorimetric assays for the determination of cell viability in cell proliferation and cytotoxicity assays

CFSE Cell Division Tracker Kit is composed of 5 vials, 100 µg per vial of CFSE (formally known as 5-(and 6)-Carboxyfluorescein diacetate succinimidyl ester of CFDA SE), and 500 µl of anhydrous DMSO. CFSE is able to passively diffuse into cells. Inside the cell, its acetate groups are cleaved by intracellular esterases, and the molecules are converted to fluorescent esters. CFSE is retained within the cell and covalently couple…

Alexa Fluor™ 555 dye

HistologiX is a leading GLP/GCP accredited Contract Research Organisation based in the UK specialising in Histology, Immunohistochemistry (IHC) and Digital Pathology services. HistologiX works with a broad range of clients from big pharma to small and medium biotech companies worldwide. Our team of scientists have in excess of 120 years combined experience and a customer retention rate of 80%. 

Supplied by IROA Technologies

Get high quality cell viability results and instant time savings

V-PLEX validated immunoassays deliver reproducible, reliable results to support the most demanding long-term studies. Offering exceptional dynamic range, high sensitivity, and lot-to-lot consistency, V-PLEX assays are available as individual analyte kits and in preconfigured and custom multiplex panels.

The HoloMonitor ® live cell imaging system enables long-term non-invasive analysis of cell cultures within your standard incubator. With the latest add-on fluorescence module, cell biologists benefit from minimizing light exposure and reducing photocytotoxicity when automatically obtaining accurate live-cell morphology, migration, proliferation data, and multi-well time-lapse videos down to a single-cell level in real-time.

Application The Cell Proliferation Reagent WST-1 is designed to be used for the nonradioactive, spectrophotometric quantification of cell proliferation and viability in cell populations using the 96-well-plate format. It can be used for: Measurement of cell proliferation in response to growth factors, cytokines, mitogens, and nutrients Analysis of cytotoxic and cytostatic compounds, such as anti-cancer drugs and other ph…