Drug discovery > Target Discovery Products & Reviews

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Biotage® Extrahera™ is an automated positive pressure workstation for column-based sample preparation in food and environmental testing. Supporting PFAS, pesticides, PCBs, PAHs, mycotoxins, and more, it handles 2 µL–50 mL volumes in plates or columns with dual-flow processing, precise pipetting, and GLP compatibility for reproducible, high-throughput results.

ultraWAVE has already revolutionized and enhanced the way analytical chemists think to sample preparation for trace metal analysis in hundreds of laboratories all over the world. ultraWAVE is based on the SRC (Single Reaction Chamber technology), invented by Milestone several years ago ( EP0728038B1 ). SRC technology achieves extraordinary performance capabilities combining microwave heating with a high-pressure reactor which…

The process of fat determination in food and feed matrices is a routine analysis still relies on outdated and matrix-dependent methods which use obsolete and time-consuming technologies. The ETHOS X offers a new approach to gravimetric fat determination, moving toward a more modern, greener and more efficient approach to total fat, Fatty Acid Methyl Ester (FAME) and free fat determinations in food and feed matrices.

Microwave-assisted solvent extraction offers superior lab efficiency in the determination of organic pollutants with microwave green extraction technique. Typical applications include chlorinated pesticides, semi-volatile organics, PAHs, PCBs, chlorinated herbicides, phenols, organophosphorus pesticides, dioxins and furans. ETHOS™ X with the fastEX-24 rotor allows the simultaneous extraction of 24 samples in 40 minutes with mi…

The ETHOS™ LEAN collects Milestone experience and embraces all these values into a compact and economical solutions for sample preparation, matching the requirements of laboratories that approach microwave digestion without the needs of high-volume labs.

The features of the new ultraWAVE 3 merge with those already intrinsic in the SRC technology so that labs will experience higher performance, greater productivity, and more streamlined workflow, providing them with improved competitiveness and a lower cost of ownership. Thanks to its superior digestion capabilities that result from its higher temperature and pressure capabilities, ultraWAVE 3 microwave system provides great…

Flexible homogenizer for rapid sample disruption

The SURFE²R 96SE is a 96 well plate-based analysis device for the measurements of electrogenic transporters (symporters, exchangers and uniporters) and pumps. It employs the label-free, SSM-based electrophysiology technology, achieving a throughput of 10,000 datapoints per day in a fully automated manner.

The SURFE²R N1 is an automated analysis device for the measurements of electrogenic transporters (symporters, exchangers and uniporters) and pumps. It employs the label-free, SSM-based electrophysiology technology, achieving a throughput of 150 datapoints per day.

Morphology driven high plex profiling on a single tissue section

The SyncroPatch 384 is a revolutionary automated patch clamp system combining high quality electrophysiological data acquisition and analysis with state-of-the-art liquid handling. With 384 amplifier channels and a 384-pipetting head, up to 384 cells can be recorded in parallel, resulting in a throughput of up to 20,000 high-quality data points per day. 

Contractility under physiological conditions

Broad portfolio of products for knockdown of gene expression

Precellys ® 24 Touch is the ideal lab homogenizer to prepare any kind of biological sample, from the softest to the hardest. It can treat up to 24 samples at a time and has been validated on more than 1,500 different samples. The intuitive touchscreen interface of Precellys ® 24 Touch makes it really easy to use. Thanks to its exclusive vacuum-based tube locking system and its specific design, Precellys ® 24 Touch is compl…

The CosMx Spatial Molecular Imager is an FFPE-compatible, single-cell imaging solution that enables researchers to investigate intact tissues through the power of spatial multiomics.

Metrohm presents Combustion IC (CIC), a fully automated system for the simultaneous determination of halogens and sulfur in widely differing matrices. With CIC, unlike with alternative methods the concentrations of the different halogens can each be shown separately. Moreover, digestion by pyrolysis is superior to offline digestion methods with regard to sample throughput and precision and correctness of results. CIC is ideal…

The Port-a-Patch is a miniaturized semi-automated patch clamp system supporting giga-seal recordings from one cell at a time. It offers fast and easy access to patch clamp data with only minimal training. Not only a powerful research tool but also ideal for educational purposes and quick tests of cells and ion channels.

The Patchliner is a fully automated patch clamp system which records from either 4 or 8 cells simultaneously. The HEKA EPC10 amplifiers, full control over the pipette speed, ability to change protocols on-the-fly and flexible add-ons for temperature control and dynamic clamp make this instrument the most versatile APC system on the market. 

Reliable Drop Setting: Reduce Costs + Increase Reproducibility The NT8 ® - Drop Setter/Crystallization Robot is a fast, nanoliter-volume liquid handler with drop dispensing capability, including setting drops for Lipidic Cubic Phase (LCP) experiments. The 8-tip head aspirates and dispenses drops from 10 nL to 1.5 μL.

The MANTIS automated liquid dispenser excels at accurate, low-volume dispensing in a wide variety of scientific workflows. The system is an easy and affordable solution to quickly increase the reproducibility and quality of your research as well as the throughput and efficiency of your laboratory. 

Build Crystallization Screens with Ease The FORMULATOR ® - Screen Builder is a next-generation liquid handler specifically designed for Protein Crystallography that uses patented microfluidic technology to dispense up to 34 different ingredients to design even the most complex optimization screens. A 96-nozzle dispensing chip can dispense any volume of any ingredient of any viscosity into any well.

The TEMPEST ®  is a high throughput, multiple reagent dispensing platform. With up-to 96 independently controllable dispensing nozzles it can be a plate-filling workhorse or a flexible assay-development partner, adapting to your needs on the fly. Used in a broad range of application areas such as cell-based and biochemical assays; molecular biology and NGS; as well as high-throughput screening.

Genizer Jacketed Liposome Extruder

The Genizer Online Extruder works with a high-pressure homogenizer to reduce the number of passes needed for optimal liposome size distribution and desired particle sizes. The homogenizer's diamond interaction chamber pre-treats the liposome sample to the nanoscale.