Drug discovery > Target Discovery Products & Reviews

A Fluorometric Method for Estimating the Number of Nonviable Cells Present in Multiwell Plates

Measure Kinase-Ligand Affinity in Live Cells The NanoBRET™ Target Engagement (TE) Intracellular Kinase Assay measures compound binding at select target kinases in intact cells. The assay is based on the NanoBRET™ System, an energy transfer technique designed to measure molecular proximity in living cells. The NanoBRET™ TE Assay measures the apparent affinity of test compounds by competitive displacement of the NanoBRET™ tra…

Simple, Plate-Based Assay for Real-Time Apoptosis Detection

Superior Size Selection and Recovery for NGS and PCR

A Simple, Non-Radioactive Assay to Measure Glucose Uptake Inside Cells

Capped or Uncapped RNA Transcripts for in vitro or in vivo Translation

Digitonin can be used in cell viability and cytotoxicity assays. It is a detergent solution useful for permeabilizing cells and for creating a cytotoxicity chemistry positive control. Supplied at 20mg/ml in DMSO

The Caspase-Glo ® 3/7 Assay System is  a highly sensitive caspase activity assay for use in plate-reader assays.

MOA-based functional bioassay to measure Fc effector activity.

A best-in-class DNA transfection reagent for your research.

Stable at Room Temperature and Easy to Use

The CellTiter 96® AQueous One Solution Cell Proliferation Assay is a colorimetric method for determining the number of viable cells in proliferation, cytotoxicity or chemosensitivity assays. The CellTiter 96® AQueous One Solution Reagent contains a tetrazolium compound [3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium, inner salt; MTS(a)] and an electron coupling reagent (phenazine ethos…

The pGEM®-T Easy Vector Systems are convienent systems to clone PCR products.   They offer all of the advantages of the pGEM®-T Vector Systems with added convieneice of recognition sites for EcoRI and NotI flankin the insertion site. Thus, several options exist to remove the desired insert DNA with a single restriction digestion. The pGEM(R)-T Easy Vectr System II contains JM109 Competent Cells in addition to all pf the…

The GSH-Glo™ Glutathione Assay is a luminescence-based assay for the detection and quantification of glutathione (GSH). The assay is based on the conversion of a luciferin derivative into luciferin in the presence of glutathione, catalyzed by glutathione S-transferase (GST). The signal generated in a coupled reaction with firefly luciferase is proportional to the amount of glutathione present in the sample. Luminescence is gen…

ultraWAVE has already revolutionized and enhanced the way analytical chemists think to sample preparation for trace metal analysis in hundreds of laboratories all over the world. ultraWAVE is based on the SRC (Single Reaction Chamber technology), invented by Milestone several years ago ( EP0728038B1 ). SRC technology achieves extraordinary performance capabilities combining microwave heating with a high-pressure reactor which…

Broad portfolio of products for knockdown of gene expression

The process of fat determination in food and feed matrices is a routine analysis still relies on outdated and matrix-dependent methods which use obsolete and time-consuming technologies. The ETHOS X offers a new approach to gravimetric fat determination, moving toward a more modern, greener and more efficient approach to total fat, Fatty Acid Methyl Ester (FAME) and free fat determinations in food and feed matrices.

Microwave-assisted solvent extraction offers superior lab efficiency in the determination of organic pollutants with microwave green extraction technique. Typical applications include chlorinated pesticides, semi-volatile organics, PAHs, PCBs, chlorinated herbicides, phenols, organophosphorus pesticides, dioxins and furans. ETHOS™ X with the fastEX-24 rotor allows the simultaneous extraction of 24 samples in 40 minutes with mi…

The VANTAstar Multi-Mode Microplate Reader is a compact multi-mode microplate reader compatible with all plate formats up to 384 wells.

The ETHOS™ LEAN collects Milestone experience and embraces all these values into a compact and economical solutions for sample preparation, matching the requirements of laboratories that approach microwave digestion without the needs of high-volume labs.

The features of the new ultraWAVE 3 merge with those already intrinsic in the SRC technology so that labs will experience higher performance, greater productivity, and more streamlined workflow, providing them with improved competitiveness and a lower cost of ownership. Thanks to its superior digestion capabilities that result from its higher temperature and pressure capabilities, ultraWAVE 3 microwave system provides great…

The FLUOstar Omega is a multimode microplate reader perfect for life science research laboratories.

LUMIstar Omega - Flexible Luminometer for Measuring Flash and Glow Luminescence

The SPECTROstar Omega microplate reader is a part of the BMG LABTECH’s family of readers that contain a CCD-based spectrometer for ultra-fast, full spectrum absorbance measurements.

The most sensitive microplate reader for high-throughput screening