Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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Digitonin

Promega Corp.

Digitonin can be used in cell viability and cytotoxicity assays. It is a detergent solution useful for permeabilizing cells and for creating a cytotoxicity chemistry positive control. Supplied at 20mg/ml in DMSO

5.0/5.0
|1 Review
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CellTiter 96® AQueous One Solution Cell Proliferation Assay (MTS)

Promega Corp.

The CellTiter 96® AQueous One Solution Cell Proliferation Assay is a colorimetric method for determining the number of viable cells in proliferation, cytotoxicity or chemosensitivity assays. The CellTiter 96® AQueous One Solution Reagent contains a tetrazolium compound [3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium, inner salt; MTS(a)] and an electron coupling reagent (phenazine ethos…

5.0/5.0
|2 Reviews
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pGEM®-T Easy Vector Systems

Promega Corp.

The pGEM®-T Easy Vector Systems are convienent systems to clone PCR products.   They offer all of the advantages of the pGEM®-T Vector Systems with added convieneice of recognition sites for EcoRI and NotI flankin the insertion site. Thus, several options exist to remove the desired insert DNA with a single restriction digestion. The pGEM(R)-T Easy Vectr System II contains JM109 Competent Cells in addition to all pf the…

4.8/5.0
|8 Reviews
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GSH-Glo™ Glutathione Assay

Promega Corp.

The GSH-Glo™ Glutathione Assay is a luminescence-based assay for the detection and quantification of glutathione (GSH). The assay is based on the conversion of a luciferin derivative into luciferin in the presence of glutathione, catalyzed by glutathione S-transferase (GST). The signal generated in a coupled reaction with firefly luciferase is proportional to the amount of glutathione present in the sample. Luminescence is gen…

5.0/5.0
|3 Reviews
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ultraWAVE SRC (Single Reaction Chamber) Microwave Digestion System

Milestone

ultraWAVE has already revolutionized and enhanced the way analytical chemists think to sample preparation for trace metal analysis in hundreds of laboratories all over the world. ultraWAVE is based on the SRC (Single Reaction Chamber technology), invented by Milestone several years ago ( EP0728038B1 ). SRC technology achieves extraordinary performance capabilities combining microwave heating with a high-pressure reactor which…

4.7/5.0
|16 Reviews
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ETHOS X microwave extraction system for fat determination

Milestone

The process of fat determination in food and feed matrices is a routine analysis still relies on outdated and matrix-dependent methods which use obsolete and time-consuming technologies. The ETHOS X offers a new approach to gravimetric fat determination, moving toward a more modern, greener and more efficient approach to total fat, Fatty Acid Methyl Ester (FAME) and free fat determinations in food and feed matrices.

5.0/5.0
|1 Review
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ETHOS X microwave extraction system for organic pollutants determination

Milestone

Microwave-assisted solvent extraction offers superior lab efficiency in the determination of organic pollutants with microwave green extraction technique. Typical applications include chlorinated pesticides, semi-volatile organics, PAHs, PCBs, chlorinated herbicides, phenols, organophosphorus pesticides, dioxins and furans. ETHOS™ X with the fastEX-24 rotor allows the simultaneous extraction of 24 samples in 40 minutes with mi…

4.7/5.0
|1 Review
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ultraWAVE 3 SRC (Single Reaction Chamber) Microwave Digestion System

Milestone

The features of the new ultraWAVE 3 merge with those already intrinsic in the SRC technology so that labs will experience higher performance, greater productivity, and more streamlined workflow, providing them with improved competitiveness and a lower cost of ownership. Thanks to its superior digestion capabilities that result from its higher temperature and pressure capabilities, ultraWAVE 3 microwave system provides great…

5.0/5.0
|3 Reviews
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Clean Screen® Xcel Well Plates

UCT, Inc.

Clean Screen® Xcel Well Plates The Clean Screen Xcel products are a line of sample prep phases designed to reduce the number of steps in the extraction, and therefore the amount of time and solvent necessary to complete the sample cleanup. Further advantages include reduced sample size and improved cleanliness and recovery. The Xcel I well plate will extract a wide array of basic drugs including benzodiazepines and opiates.…

5.0/5.0
|1 Review
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Positive Pressure Manifold

UCT, Inc.

Positive Pressure Manifold - A simple, robust way to quickly process up to 48 samples at one time. The Positive Pressure Manifold can accommodate a multitude of column sizes and provides even flow to each position. Positive Pressure Manifold Features: All 48 positions are individually regulated to provide even pressure to each column. There are four banks of 12 positions each. The user can control flow to each of the four…

4.9/5.0
|3 Reviews
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