Drug discovery > Target Discovery Products & Reviews

Automate your scientific workflow easily with the Thermo Scientific™ Spinnaker™ 3 Microplate Mover robot. This latest addition to our add-and-go lab automation ecosystem promotes automation adoption by users of any experience level through unmatched ease of use and reliability. 

NEBNext® reagents are a series of highly pure reagents that facilitate library preparation of DNA or RNA for downstream applications such as next generation sequencing and expression library construction. Available in sets, master mixes and modules, these robust reagents undergo stringent quality controls and functional validation, ensuring maximum yield, convenience and value. Advantages of NEBNext Reagents for RNA Library Pr…

Q5® Site-Directed Mutagenesis Kit enables rapid, site-specific mutagenesis of double-stranded plasmid DNA in less than 2 hours. The kit utilizes the robust Q5 Hot Start High-Fidelity DNA Polymerase along with custom mutagenic primers to create insertions, deletions and substitutions in a wide variety of plasmids. After PCR, the amplified material is added directly to a unique Kinase-Ligase-DpnI (KLD) enzyme mix for rapid, roo…

The NEBNext® DNA Library Prep Master Mix Set for Illumina® contains enzymes and buffers in convenient master mix formulations that are ideally suited for sample preparation for next-generation sequencing, and for preparation of expression libraries. NEBNext® reagents are a series of highly pure reagents that facilitate sample preparation of DNA or RNA for downstream applications such as next generation sequencing and expressi…

he NEBNext® Ultra™ DNA Library Prep Kit for Illumina contains enzymes and buffers that are ideal to convert a small amount of DNA input into indexed libraries for next-generation sequencing on the Illumina platform (Illumina, Inc). The workflow of NEBNext Ultra DNA Library Prep Kit for Illumina is very user-friendly and fast with minimal hands-on time.NEBNext® reagents are a series of highly pure reagents that facilitate samp…

NEBNext® dsDNA Fragmentase® generates dsDNA breaks in a time-dependent manner to yield 100–800 bp DNA fragments depending on reaction time. NEBNext dsDNA Fragmentase contains two enzymes, one randomly generates nicks on dsDNA and the other recognizes the nicked site and cuts the opposite DNA strand across from the nick, producing dsDNA breaks. The resulting DNA fragments contain short overhangs, 5´-phosphates, and 3´-hydroxyl…

The NEBNext® mRNA Library Prep Master Mix Set for Illumina® contains enzymes and buffers that are ideally suited for sample preparation for next-generation sequencing, and for preparation of expression libraries. NEBNext® reagents are a series of highly pure reagents that facilitate sample preparation of DNA or RNA for downstream applications such as next generation sequencing and expression library construction. The reagents…

Flexible homogenizer for rapid sample disruption

ultraWAVE has already revolutionized and enhanced the way analytical chemists think to sample preparation for trace metal analysis in hundreds of laboratories all over the world. ultraWAVE is based on the SRC (Single Reaction Chamber technology), invented by Milestone several years ago ( EP0728038B1 ). SRC technology achieves extraordinary performance capabilities combining microwave heating with a high-pressure reactor which…

Broad portfolio of products for knockdown of gene expression

The process of fat determination in food and feed matrices is a routine analysis still relies on outdated and matrix-dependent methods which use obsolete and time-consuming technologies. The ETHOS X offers a new approach to gravimetric fat determination, moving toward a more modern, greener and more efficient approach to total fat, Fatty Acid Methyl Ester (FAME) and free fat determinations in food and feed matrices.

Microwave-assisted solvent extraction offers superior lab efficiency in the determination of organic pollutants with microwave green extraction technique. Typical applications include chlorinated pesticides, semi-volatile organics, PAHs, PCBs, chlorinated herbicides, phenols, organophosphorus pesticides, dioxins and furans. ETHOS™ X with the fastEX-24 rotor allows the simultaneous extraction of 24 samples in 40 minutes with mi…

Precellys ® 24 Touch is the ideal lab homogenizer to prepare any kind of biological sample, from the softest to the hardest. It can treat up to 24 samples at a time and has been validated on more than 1,500 different samples. The intuitive touchscreen interface of Precellys ® 24 Touch makes it really easy to use. Thanks to its exclusive vacuum-based tube locking system and its specific design, Precellys ® 24 Touch is compl…

The ETHOS™ LEAN collects Milestone experience and embraces all these values into a compact and economical solutions for sample preparation, matching the requirements of laboratories that approach microwave digestion without the needs of high-volume labs.

The features of the new ultraWAVE 3 merge with those already intrinsic in the SRC technology so that labs will experience higher performance, greater productivity, and more streamlined workflow, providing them with improved competitiveness and a lower cost of ownership. Thanks to its superior digestion capabilities that result from its higher temperature and pressure capabilities, ultraWAVE 3 microwave system provides great…

Clean Screen® Xcel Well Plates The Clean Screen Xcel products are a line of sample prep phases designed to reduce the number of steps in the extraction, and therefore the amount of time and solvent necessary to complete the sample cleanup. Further advantages include reduced sample size and improved cleanliness and recovery. The Xcel I well plate will extract a wide array of basic drugs including benzodiazepines and opiates.…

Positive Pressure Manifold - A simple, robust way to quickly process up to 48 samples at one time. The Positive Pressure Manifold can accommodate a multitude of column sizes and provides even flow to each position. Positive Pressure Manifold Features: All 48 positions are individually regulated to provide even pressure to each column. There are four banks of 12 positions each. The user can control flow to each of the four…

Our 96 Deep Well Plates are made from solvent resistant, low extractable polypropylene. Standard frits are polyethylene with 20μm pores. The 2mL well provides capability for methods that require a larger sample size. The separate wells and greater capacity eliminate well-to-well carry over. We offer disposable plates compatible with Beckman, Caliper, Gilson, Hamilton, PerkinElmer and Tecan liquid handling systems. 96 Deep Wel…

Abalone derived enzyme. Available in both liquid and lyophilized forms. Liquid enzyme activity > 100,000 Units/mL - Lyophilized enzyme activity 1,000,000 - 3,200,000 Units/g

Live-cell analysis system

Fast, accurate, and automated brightfield and fluorescent cell counting

Lux3 BR is a small brightfield live-cell imager, equipped with a high-quality 6.4 MP CMOS camera. It is designed to work inside a standard cell culture incubator without disturbing temperature, airflow, and optimum culture conditions. Detailed brightfield images can be captured using the new device. In both x- and y-direction, 2072 pixels combined with 1.45 mm field of view provide a resolution of 0.7 µm/pixel. 

High-throughput live-cell analysis system

The Omni FL is a fluorescence (green and red) and brightfield microscope designed to image live cells directly inside a cell culture incubator. The device can be used for continuous cell culture monitoring, as well as endpoint assays. Applications: cell viability, transfection efficiency, co-culture analysis, and more.

The Specac Mini-Pellet Press is an entry-level laboratory hydraulic press for the preparation of high-quality 7mm KBr pellets for transmission FTIR analysis. With a rugged and durable design, this press is intended for regular laboratory use with maintenance-free operation. Specac’s Mini-Pellet Press is designed to be used on a laboratory benchtop, but is small in size and light enough in weight to allow it to be moved to d…