Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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AssayMAP Peptide Sample Preparation

Agilent Technologies

The Agilent AssayMAP Peptide Sample Prep digests, cleans and optionally fractionates samples for peptide mapping and biomarker analysis workflows. The solution combines best-in-class automation and chromatographic methods to radically reduce variability and allow quick method development. C18, underivitized polystyrene and strong cation exchange resins are available for cleanup and fractionation.AssayMAP Peptide Sample Prepar…

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SureTag Complete DNA Labeling Kit

Agilent Technologies

SureTag Labeling Kits provide all necessary reagents for efficient sample fragmentation, enzymatic labeling and clean-up. The SureTag DNA Labeling Kits generate robust cyanine-labeled genomic DNA targets for optimal hybridization signals with high signal-to-noise ratio and low probe-to-probe variability.

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HER2 IQFISH pharmDx™

Agilent Technologies

HER2 IQFISH pharmDx™ is a direct fluorescence in situ hybridization (FISH) assay based on Dako's new fast IQISH hybridization buffer chemistry. The new IQISH hybridization buffer is non-toxic and allows genomic DNA probe hybridization to be performed in just 60-120 minutes. The short hybridization time results in a turnaround time of about 3½ hours for a complete FISH staining from deparaffinization to mounting. HER2 IQFISH p…

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TOP2A IQFISH pharmDx™

Agilent Technologies

TOP2A IQFISH pharmDx™ is a direct fluorescence in situ hybridization (FISH) assay based on Dako's new fast IQISH hybridization buffer chemistry. The new IQISH hybridization buffer is non-toxic and allows genomic DNA probe hybridization to be performed in just 60-120 minutes. The short hybridization time results in a turnaround time of about 3½ hours for a complete FISH staining from deparaffinization to mounting. TOP2A IQFISH…

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SureSelect Focused Exome

Agilent Technologies

The SureSelect Focused Exome is a highly targeted design that enables analysis of only disease-associated targets, enabling superior coverage of disease-associated regions even on benchtop sequencers. This design provides 20 or more reads for 95% of targets at 1.5Gb (100x) of sequencing and 98% of targets with 3Gb (200x) of sequencing.

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Mycotoxins PCDL

Agilent Technologies

Perform truly comprehensive mycotoxin screening applications with the Mycotoxins and Related Metabolites Personal Compound Database and Library (PCDL) for TOF and Q-TOF LC/MS systems. Detailed acquisition method setup information allows fast ramp-up to full productivity.

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Pesticides tMRM Database for Triple Quadrupole LC/MS

Agilent Technologies

The Pesticide tMRM Database for LC/QQQ system contains a curated database with over 750 compounds, with up to 10 MRM transitions, fragmentor voltages, and collision energies for each compound. Instantly build methods for targeted screening and confident quantitation for hundreds of analytes in a single run. Features: Benefit from seamless integration of the tMRM database into Agilent MassHunter Quantitative software f…

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Veterinary Drug PCDL for LC/TOF and LC/Q-TOF

Agilent Technologies

The Veterinary Drug Personal Compound Database and Library (PCDL) for TOF or Q-TOF LC/MS systems contains a curated accurate-mass database with over 2,100 compounds, accurate-mass MS/MS spectra for more than 1,500 compounds, and retention time information for 120 compounds. Detailed acquisition method setup information provided allows for fast ramp-up to full productivity.

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MassHunter Profinder Software

Agilent Technologies

Profinder is a fast, batch-processing feature extraction software for differential analysis that supports data from Agilent GC/MSD, GC/Q-TOF, LC/TOF and LC/Q-TOF instruments. Profinder speeds up differential and flux analysis workflows using an intuitive user interface.

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Thermal Separation Probe

Agilent Technologies

The Agilent Thermal Separation Probe (TSP) provides fast analysis of solid, liquid, and slurry samples. The process is simple, clean, and requires limited or zero sample preparation. Non-vaporized high boiling point ‘dirty sample matrix’– compounds, which can contaminate the GC liner and column, remain inside the micro-vial, and can be discarded after each injection. Use the TSP when testing complex samples in food, forensics,…

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