Separations Products & Reviews

Our pre manufactured custom ACT beads for your in-house coupling of ligands. Any ligand containing amino groups or thiols, e.g. proteins and peptides can be covalently bound to the beads using a simple process. All steps are performed at physiological conditions and room temperature, without using any hazardous reagents or organic solvents. After coupling of the ligand, the magnetic beads can be used for affinity purification…

Custom-design for your application. MAGic Bioprocessing are specialized in the development and production of tailor-made magnetic bead products for a variety of different applications.

MAGic™Accio PILOT perfectly supports the development phase, medium-scale processing of nucleic acids, peptides, proteins, such as antibodies and viruses from clarified- or unclarified cell-culture mixtures. The separation is performed in sample volumes from 5 ml up to a couple of liters. The use of the MAGic™Accio PILOT 50, MAGic™Accio PILOT 500 and MAGic™Accio PILOT 2000 together with 20µl – 250ml of settled MAGic™Beads offer…

MAGic™Accio PROCESS are our large fully automated magnetic separator systems, made for efficient capture of 1-40 liters of MAGic™Beads magnetic beads from large volumes of complex feedstocks. During the production phase of biopharmaceuticals, large-scale recovery of the product from an unclarified cell-culture is performed in a one-step clarification and purification by using the proprietary designed MAGic™Accio PROCESS units…

MAGic™Accio LAB are designed for research lab, small-scale processing of nucleic acids, peptides, proteins, antibodies or viruses from crude sample mixtures like serum, whole blood, ascites, food-samples or unclarified cell cultures performed in volumes from 100 µl to 2 ml. Utilizing 10-200 µl of MAGicBeads together with the MAGicAccio LAB cube or LAB rack enables fast, reliable and easy separation of up to 6 mg of proteins pe…

TSKgel Phenyl-3PW (20) process resin provides a novel solution for the purification of oligonucleotides. This resin is capable of cleaving DMT protective groups on-column in order to streamline downstream bioprocessing of complex oligo species.

TOYOPEARL Super A is a novel, robust protein A resin designed to efficiently purify mAbs and other antibody species like ADCs and bispecifics. This resin offers high alkaline stability, exceptional dynamic binding capacity, and a polymer base bead able to withstand high linear velocities.

TSKgel HIC-ADC columns are novel analytical solutions to rapidly characterize the drug-antibody ratio (DAR) for antibody drug conjugates (ADCs). Available in butyl and phenyl hydrophobicities with additions to the column family on the way, the TSKgel HIC-ADC column line has you covered for fast ADC analysis.

Innovative solution that enables investigation of multiple critical attributes for LNP drug products, without extensive sample preparation or dye requirements.

A tool for chromatographic purification of LNPs as an alternative to filtration methods.

The patent-pending EXP® Trap Column is rated for use at 20,000+ psi (1,400+ bar). This unique design connects directly to any injection valve (with 10-32 threads) or in-line with 1/16” stainless tubing for unparalleled convenience and efficiency. The EXP® Cartridge System enables chemists to quickly remove detergents or salts which can affect the ionization process in MS work. This trapping technique can concentrate the sampl…

OPTI-MAX® Cartridge Check Valves are designed to offer maximum performance and ease of use. From the sharp, consistent threads on OPTI-MAX® custom housings, to the exacting standards used to match ball/seat sets in OPTI-MAX® cartridges, every aspect of design and manufacturing reflects an unavoidable fact: when it comes to reliable check valve operation, quality and precision make a big difference. OPTI-MAX® check valves offer…

The entire EXP® Stem Trap and reusable holder are only slightly larger than a standard HPLC fitting. Its slim architecture allows it to easily fit into crowded instrument compartments or to connect directly to tightly-spaced injection ports. When tightened by hand, the EXP® Stem Trap seals to 8,700+ psi. All configurations incorporate wrench-flats to enable flawless sealing to 20,000+ psi (1,400+ bar). The unique packed floati…

The EXP® Fitting System is the premier adjustable nut and ferrule compression fitting for extreme high-pressure connections between 1/16" tubing and any 10-32 port. The patent-pending Titanium Hybrid Ferrule integrates the resilience of titanium with the proven sealing ability of PEEK in a superb one-piece design. The Hybrid Ferrule provides a perfect seal with every connection, yet the swage can be released without tools to a…

The EXP® Hex Head Nut & Titanium Hybrid Ferrule fitting system is the premier adjustable nut and ferrule compression fitting for extreme high-pressure connections between 1/16" tubing and any 10-32 port. The patent-pending Titanium Hybrid Ferrule integrates the resilience of titanium with the proven sealing ability of PEEK in a superb one-piece design. The Hybrid Ferrule provides a perfect seal with every connection, yet the s…

The EXP® Hand Tight Coupler is the premier adjustable nut and ferrule compression fitting for extreme high-pressure connections between 1/16" tubing and any 10-32 port. The patent-pending Titanium Hybrid Ferrule integrates the resilience of titanium with the proven sealing ability of PEEK in a superb one-piece design. The Hybrid Ferrule provides a perfect seal with every connection, yet the swage can be released without tools…

The EXP® Stem Filter features a choice of frit porosities integrated with our patented auto-adjusting stem for repeated ZDV connections with any 10-32 port. The entire filter stem and reusable holder are only slightly larger than a standard HPLC fitting. This slim architecture allows it to easily fit into crowded instrument compartments, tightly spaced injection ports, and anywhere else you need an extra level of protection ag…

The EXP® Nano Trap System is designed to remove detergents or salts which can affect the ionization process in MS work rated for routine use up to 20,000 psi.The new nano-scale traps are available in two formats – EXP® Nano Trap and EXP® Nano Trap HR. Both formats are available in 10 or 20 mm lengths and in a variety of bed volumes ranging from 0.25µL - 4.0µL. The EXP® Nano Trap follows a traditional trap column format, design…

The EXP® Hand Tight Nano Fittings System offers hand-tight and hex head adjustable nut and ferrule compression fittings for extreme pressure connections between 1/32” stainless steel tubing and 6-40 ports.Ideal for nano-scale UHPLC and UHPLC/MS, this nut and ferrule compression fitting is rated to 20,000+ psi (1400+ bar). The patent-pending EXP® 1/32” Titanium Hybrid Ferrule combines the sealing capability of PEEK and robust n…

The EXP® Nano Fittings System offers hand-tight and hex head adjustable nut and ferrule compression fittings for extreme pressure connections between 1/32” stainless steel tubing and 6-40 ports.Ideal for nano-scale UHPLC and UHPLC/MS, this nut and ferrule compression fitting is rated to 20,000+ psi (1400+ bar). The patent-pending EXP® 1/32” Titanium Hybrid Ferrule combines the sealing capability of PEEK and robust nature of ti…

OPTI-MAX® Cartridge Check Valves are designed to offer maximum performance and ease of use. From the sharp, consistent threads on OPTI-MAX® custom housings, to the exacting standards used to match ball/seat sets in OPTI-MAX® cartridges, every aspect of design and manufacturing reflects an unavoidable fact: when it comes to reliable check valve operation, quality and precision make a big difference. OPTI-MAX® check valves offer…

OPTI-SOLV® Reservoir Filters employ a unique conical design inside the filter housing to prevent air bubbles from getting trapped and disturbing your analysis. While the availability of HPLC-grade solvents diminishes the need for pre-filtering, it is still imperative that a filtration device be installed in the reservoir. Placing a filter in the reservoir is an economical way to filter particles that may result from buffer sal…

A solid PTFE body keeps OPTI-SOLV® filter at the base of the bottle where a bottom-mounted titanium frit provides unrestricted solvent access. As always, Optimize makes installation as simple as possible - no tools or fittings required and includes 5 feet of pre-installed PTFE tubing. OPTI-SOLV Reservoir Filters employ a unique conical design inside the filter housing to prevent air bubbles from getting trapped and disturbing…

The OPTI-SOLV® Mini Filter provides low-impact filtration in a package no larger than a finger tight fitting. Use them to extend the life of your analytical column, or before your mass spectrometer as a last line of defense against debris. Perfect zero-dead-volume connections are obtained every time with our patented automatic tube stop depth adjustment. Unique depth-filtering elements allow for greater capacity with no band s…

The OPTI-SOLV® Nano Filter follows our Micro Filter but cuts the internal volume down even further. With less than 50 nL of internal volume, the OPTI-SOLV® Nano Filter is ideal for mass spectrometry to protect your electrospray and nanospray tips from clogging with debris. Like the Micro and Mini Filter, the Nano Filter is designed to be used in today's low volume, high sensitivity chromatographic applications as a last line o…