Drug discovery > Pre-Clinical Development Products & Reviews

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Products, services, reviews and techniques used in lead molecule delivery, formulation and toxicology, using assays and animal models.

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Disposable Cuvettes for Spectroscopy

Kartell S.p.A.

Disposable cuvettes for spectrophotometry, optical PS visible range cuvettes, UV Grade PMMA cuvettes. Standard and semi-micro disposable cuvettes for spectroscopy made of optical PS and PMMA UV grade optical windows to achieve optimal transmittance through spectral range from 340 to 800 nm (OPS) an from 280 to 800 nm (PMMA UV qrade). The engineering and quality control determine the reproducibility of the cuvettes. These are s…

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BD FocalPoint™

Source BioScience

The BD FocalPoint™ is an automated imaging system that can assist in the primary screening of BD SurePath™ liquid based cytology slides and is currently used worldwide. Up to 288 slides can be loaded onto the system at the same time with the capacity to load additional slides during the working day. The system can operate 24 hours continually over a 7 day period and is monitored remotely by the manufacturer Becton Dickinson v…

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FlowCellect™ Human NK Cell Characterization Kit

Merck

The FlowCellect™ Human NK Cell Characterization Kit includes three directly conjugated antibodies, Anti-CD3-APC, Anti-CD56-PE, and Anti-CD16 FITC. This three color kit is designed to characterize NK within mixed cell populations. The antibodies provided have been carefully titrated to ensure the ability to accurately measure the expression of all markers simultaneously. Sufficient reagents are provided to perform 25 three-colo…

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iReport™- Understand your expression data

Ingenuity Systems Inc.

The fastest way to understand the biological meaning of your expression data Rapidly Identify Biologically Compelling Transcript Changes:Ingenuity® iReport™ is an interactive web-based report, optimized for gene expression experiments from – RNA-Seq, microarray, and real-time PCR platforms, that provides a fast and accurate biological and statistical analysis of your experimental data.

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iCell Hepatocytes

Cellular Dynamics International

iCell® Hepatocytes, derived from human induced pluripotent stem (iPS) cells, provide access to commercial quantities of high quality, high purity human liver cells for preclinical drug discovery, hepatotoxicity testing, and disease research. iCell® Hepatocytes express alpha-1-antitrypsin (AAT), asialoglycoprotein receptor (ASGR1), hepatocyte nuclear factor 4 alpha (HNF4A), and secrete albumin at levels similar to adult primary…

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FlowCellect™ Cell Cycle Checkpoint H2A.X DNA Damage Kit

Merck

Millipore’s FlowCellect™ DNA Damage (Histone H2A.X) and Cell Cycle Analysis Kit is designed to identify the linkage between DNA damage in relation to cell cycle checkpoints in flow cytometry applications. The kit includes a directly conjugated Anti-phospho-Histone H2A.X (Ser139) Alexa Fluor® 488 antibody plus a DNA dye (Propidium Iodide) which allows the researcher to perform bivariate analysis to identify where DNA damage ta…

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FlowCellect™ Cell Cycle Checkpoint ATM DNA Damage Kit

Merck

Millipore’s FlowCellect™ DNA Damage (ATM) and Cell Cycle Analysis Kit is designed to identify the linkage between DNA damage in relation to cell cycle checkpoints in flow cytometry applications. The kit includes a directly conjugated Anti-phospho-ATM (Ser1981) Alexa Fluor® 488 conjugate plus a DNA dye (Propidium Iodide) which allows the researcher to perform bivariate analysis to identify where DNA damage takes place relativ…

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FlowCellect™ Bivariate Cell Cycle Kit for DNA Replication Analysis

Merck

Millipore’s FlowCellect™ Bivariate Cell Cycle Kit for DNA Replication Analysis is designed to investigate cells undergoing replication in S-phase of the cell cycle with high accuracy and confidence in flow cytometry applications. The kit includes a directly conjugated Anti-BrdU Alexa Fluor® 488 conjugate plus a DNA dye (Propidium Iodide) which allows the researcher to perform bivariate analysis to distinguish cells in two dim…

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FlowCellect™ Bivariate Cell Cycle Kit for G2/M Analysis

Merck

Millipore’s FlowCellect™ Bivariate Cell Cycle Kit for G2/M Analysis is designed to allow the researcher to easily identify, discriminate, and quantitate cells between the G2 and M-phases of the cell cycle. The kit can be used to perform bivariate analysis to measure cell cycle distributions by discrimination of cell cycle phases without the need of sophisticated software modules or algorithms. Having the ability to distingui…

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FlowCellect™ Multi-Color DNA Damage Response Kit

Merck

Millipore’s FlowCellect™ Multi-Color DNA Damage Response Kit is designed to enable a researcher a quick and easy way to detect the phosphorylation state of ATM, SMC1 and Histone H2A.X by flow cytometry. Millipore’s FlowCellect™ Multi-Color DNA Damage Response Kit was developed and tested using the DNA damaging reagent, Etoposide, in HeLa cells as a model system but the kit can be used with other human cell lines to determine…

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Rocket 4D Synergy Large Volume Evaporator

Genevac

Rocket 4D Synergy is designed primarily to evaporate large sample volumes, with autofeed if required, allowing automatic evaporation of volumes up to 100 litres. Rocket 4D Synergy provides fast, safe evaporation for solvents with a boiling point of up to 165°C (DMF) and can easily dry aqueous samples. The system feeds the solution for evaporation to the evaporation vessel, controls temperature and pressure, prevents bumping…

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GeSiM Nano-Plotter™ Non-Contact Nanolitre Dispenser

Analytik Ltd

The Nano-Plotter™ series are ideal for generating high-quality spots by non-contact dispensing of sub-nanolitre volumes. The highly versatile “drop on demand” piezoelectric technology allows the placement of drops onto a variety of substrates with outstanding precision, and also the mixing of samples into pre-filled cavities to run nano-assays. These compact instruments are your ideal solution for the development and producti…

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DNAQual Kit

Eurobio Laboratories

DNAQual kit is used for the quantitative assessment of DNA degradation by quantifying the number of copies of a target gene compared to a calibrator gene (included in the kit) in any human DNA sample by qPCR in duplex in 90 minutes. The two genes (target and calibrator are measured with two specific probes carrying each a different fluorophore: Texas Red for the calibrator and VIC for the target gene. The software on the qPCR…

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Accelrys Enterprise Platform

Accelrys

The Accelrys Enterprise Platform is a unique, scientifically-aware software platform that enhances organizational efficiency, improves collaboration and speeds innovation in lab-to-plant processes, enabling organizations to bring better products to market more quickly and efficiently. The Accelrys Enterprise Platform provides: ■ Application Services ■ Development Services ■ Data Management Services ■ IT Services ■ Scientific a…

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