Drug discovery > Pre-Clinical Development Products & Reviews

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Products, services, reviews and techniques used in lead molecule delivery, formulation and toxicology, using assays and animal models.

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IRDye Click Chemistry Reagents

LICORbio

IRDye® Click Chemistry reagents (DBCO, Alkyne, and Azide) offer convenient, versatile and reliable methods for biomolecule labeling. With a variety of in vitro and in vivo applications, from biomarker isolation to assay development.

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Afla-V AQUA

Waters

Afla-V AQUA Strip Tests utilize the proven sensitivity and selectivity of VICAM's monoclonal antibodies to accurately detect and measure total aflatoxins (B1, B2, G1 & G2) at levels as low as 2.5 ppb and as high as 50 ppb. Afla-V AQUA eliminates the need for hazardous solvents using a water-based, dilution-free extraction procedure that develops in just 5 minutes. Results are displayed on the digital screen and may also be pr…

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PoraPak Rxn

Waters

Waters offers PoraPak™ Rxn, a family of polymer-based chromatography products for superior cleanup of synthetic reactions. PoraPak Rxn products are available in two chemistries: PoraPak Rxn CX, a strong cation-exchange sorbent and PoraPak Rxn RP, a reversed-phase sorbent.PoraPak Rxn sorbents are based on copolymers that exhibit the following properties:Hard material that does not develop increasing back pressure with flowLitt…

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DisQuE Dispersive Sample Preparation Kit

Waters

DisQuE Dispersive Sample Preparation is a well proven, high throughput sample preparation method for a wide array of pesticides in produce. The kit contains conveniently packaged vials with pre-measured sorbents and buffers used to provide extraction and clean-up for up to 100 samples. Each 50 mL DisQuE Extraction tube contains 6 grams of magnesium sulphate and 1.5 grams of sodium acetate. Each 2 mL DisQuE Clean-Up tube cont…

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BRANDplates® Strip Plates for ELISA Applications

BRANDTECH® Scientific, Inc.

Adaptable Microplate Solution for Custom ELISA Applications. BRANDplates® Strip Plates are especially suited for laboratories designing custom ELISA applications, or desiring increased flexibility in their ELISA application. To ensure the effective binding of a wide range of antigens or antibodies to the microplate surface, the strip plates are available in two treatment types: pureGrade™ or immunoGrade™. The pureGrade™ plate…

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Liquid Handling Station

BRANDTECH® Scientific, Inc.

The BRAND Liquid Handling Station pipetting robot handles routine tasks at high speed and with the highest precision. The LHS closes the gap between electronic pipettes and highly complex, expensive pipetting robots. It is a quiet and compact instrument with a unique front door allowing it be set up in tight quarters. The instrument has 7 working positions and 5 available liquid ends with single channel volumes up to 1000uL an…

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Lyovapor™ L-300

BUCHI

With Infinite-Technology™ the Lyovapor™ L-300 is the first continuous sublimation system available on the market. The instrument contains two alternating condensers that operate at -105 °C and undergo automatic hygenic cleansing. In addition, Infinite-Control™ allows entire process control of all relevant parameters via mobile devices or a stationary computer.

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SpeedDigester K-439

BUCHI

Fully automated IR digestion due to precise temperature control The automatic SpeedDigester K-439 features precise temperature control and an easy to read graphical display which allow for an easy and automated digestion process and uniform, standardized sample processing. The complete digestion process occurs through precise temperature/time control. The temperature control makes it possible to verify the temperature with an…

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Cyto-Surf® B

Sphere Bio

Cyto-Surf® B is required to operate Cyto-Mine®. It provides the surfactant necessary to make stable biocompatible picodroplets and is fully optimized for Cyto-Mine®.

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Cyto-Cartridges®

Sphere Bio

Cyto-Cartridge® provides the core microfluidic functions used by Cyto-Mine® to implement picodroplet workflows. It is a single-use, fully disposable device to ensure zero cross-contamination between runs and maintain cell quality.

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96 VVP Volume Verified Pipetting Channel Pipetting Head

Dynamic Devices

The Lynx Series Liquid Handling Robot's new 96 VVP head with Volume Verified Pipetting (VVP) offers the first air based 96 head with verified individual volumes in each channel. VVP implements real-time liquid handling feedback through the use of in-line flow sensors that exactly measure the volume of liquid being aspirated/dispensed in the tip. The actual volumetric measurement accommodates for liquid viscosity and temperatu…

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EXP® Trap Columns

Optimize Technologies, Inc.

The patent-pending EXP® Trap Column is rated for use at 20,000+ psi (1,400+ bar). This unique design connects directly to any injection valve (with 10-32 threads) or in-line with 1/16” stainless tubing for unparalleled convenience and efficiency. The EXP® Cartridge System enables chemists to quickly remove detergents or salts which can affect the ionization process in MS work. This trapping technique can concentrate the sampl…

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EXP® Stem Trap

Optimize Technologies, Inc.

The entire EXP® Stem Trap and reusable holder are only slightly larger than a standard HPLC fitting. Its slim architecture allows it to easily fit into crowded instrument compartments or to connect directly to tightly-spaced injection ports. When tightened by hand, the EXP® Stem Trap seals to 8,700+ psi. All configurations incorporate wrench-flats to enable flawless sealing to 20,000+ psi (1,400+ bar). The unique packed floati…

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EXP® Stem Filter

Optimize Technologies, Inc.

The EXP® Stem Filter features a choice of frit porosities integrated with our patented auto-adjusting stem for repeated ZDV connections with any 10-32 port. The entire filter stem and reusable holder are only slightly larger than a standard HPLC fitting. This slim architecture allows it to easily fit into crowded instrument compartments, tightly spaced injection ports, and anywhere else you need an extra level of protection ag…

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EXP® Nano Trap

Optimize Technologies, Inc.

The EXP® Nano Trap System is designed to remove detergents or salts which can affect the ionization process in MS work rated for routine use up to 20,000 psi.The new nano-scale traps are available in two formats – EXP® Nano Trap and EXP® Nano Trap HR. Both formats are available in 10 or 20 mm lengths and in a variety of bed volumes ranging from 0.25µL - 4.0µL. The EXP® Nano Trap follows a traditional trap column format, design…

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OPTI-SOLV® Solvent Reservoir Filter

Optimize Technologies, Inc.

OPTI-SOLV® Reservoir Filters employ a unique conical design inside the filter housing to prevent air bubbles from getting trapped and disturbing your analysis. While the availability of HPLC-grade solvents diminishes the need for pre-filtering, it is still imperative that a filtration device be installed in the reservoir. Placing a filter in the reservoir is an economical way to filter particles that may result from buffer sal…

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OPTI-SOLV® Biocompatible Solvent Reservoir Filter

Optimize Technologies, Inc.

A solid PTFE body keeps OPTI-SOLV® filter at the base of the bottle where a bottom-mounted titanium frit provides unrestricted solvent access. As always, Optimize makes installation as simple as possible - no tools or fittings required and includes 5 feet of pre-installed PTFE tubing. OPTI-SOLV Reservoir Filters employ a unique conical design inside the filter housing to prevent air bubbles from getting trapped and disturbing…

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OPTI-SOLV® In-Line Hand-Tight Filter System

Optimize Technologies, Inc.

The user-friendly Hand-Tight OPTI-SOLV® In-Line Filter System is well suited for a number of applications, such as high temperature, high-pressure environments where quick changes are imperative. The unique swivel design allows frits to be changed without removing the connecting tubing. Just plumb it once and leave it. The frictional forces generated at the piston/seal interface inevitably lead to particulate shedding. Placeme…

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