Drug discovery > Pre-Clinical Development Products & Reviews

The CellTox™ Green Cytotoxicity Assay measures changes in membrane integrity that occur as a result of cell death. The assay is intended to assess cytotoxicity in cell culture after experimental manipulation. The assay system uses a proprietry asymmetric cyanine dye that is excluded from viable cells but preferentially stains the DNA from dead cells. When the dye binds DNA released from cells, its fluorescence properties are s…

The CellTiter-Glo® 3D Cell Viability Assay is a homogeneous method to determine the number of viable cells in 3D cell culture based on quantitation of the ATP present, which is a marker for the presence of metabolically active cells.   This ready-to-use reagent is based on the original CellTiter-Glo® Luminescent Cell Viability Assay chemistry and eliminates the need to combine buffer with lyophilized substrate when prepa…

The RealTime-Glo™ MT Cell Viabiilty Assay measures viability of cells in a non-lytic, real-time live-cell format, saving time, cells and reagent costs.

The CellTiter-Blue® Cell Viability Assay provides a homogeneous, fluorescent method for monitoring cell viability. The assay is based on the ability of living cells to convert a redox dye (resazurin) into a fluorescent end product (resorufin). Nonviable cells rapidly lose metabolic capacity and thus do not generate a fluorescent signal. The homogeneous assay procedure involves adding the single reagent directly to cells cultur…

The Promega CytoTox 96® Non-Radioactive Cytotoxicity Assay is a colorimetric alternative to radioactive cytotoxicity assays. The CytoTox 96® Assay quantitatively measures lactate dehydrogenase (LDH), a stable cytosolic enzyme that is released upon cell lysis, in much the same way as [51Cr] is released in radioactive assays. Released LDH in culture supernatants is measured with a 30-minute coupled enzymatic assay that result…

The Specac flagship Autotouch Press is designed for high volume laboratory sample preparation for XRF and other elemental analysis techniques, capable of pressing a single sample in under two minutes when augmented with the Apex automated die system.

A fully-integrated turnkey Anesthesia System immobilizes small animals when taking pictures with the iBox Explorer2 Imaging Microscope, iBox® Scientia™, and iBox® Spectra™ Imaging System.   

Ergonomic upright microscopes with eco-illumination for clinical and laboratory applications.

Flexible software platform for controlling Nikon microscopes and 3rd-party components, with powerful custom programming tools for image acquisition and analysis.

The CyFlow® Counter is a fully equipped portable and ultra-compact desktop flow cytometer.

Family of ultra-compact, high-end, multi-laser, benchtop flow cytometry systems.

The Sci-Print VX2 is a fully automated tube labeling system, capable of printing and applying labels to tubes ranging from 0.5 mL to 50 mL in size. The system can be used stand-alone or configured to sort racked tubes, receive bulk tubes, uncap/recap, fill and/or scan barcodes.

Leica DM2500 & DM2500 LED optical microscopes are tools for demanding tasks in life science routine and research applications. With their transmitted light illumination, optical performance, and state-of-the-art accessories, they are especially well-suited for challenging life science research tasks that require differential interference contrast or high-performance fluorescence.

MOLECULAR OPTICAL IMAGING THAT FITS YOUR RESEARCH

96 well ELISA microplates

ISOLUTE SLE+ Supported Liquid Extraction plates and columns offer an efficient alternative to traditional liquid-liquid extraction (LLE) for bioanalytical sample preparation, extracting up to 400 µL aqueous sample.

Isolera, a compact flash purification system with intelligent features, enables chemists to easily achieve better separations. The patented TLC-to-gradient feature automatically creates elution gradients and suggests cartridge and sample size. Collect fractions using two wavelengths, adjust the flow rate from 1 to 200 mL/min as needed and use up to four solvents in a single gradient, for maximum purity and yield.

PhyTip® Columns offer automated, flexible and scalable solution for biomolecule separation. The PhyTip® technology platform enables chromatography using automated bench top platforms (for up to 12 samples in parallel) and robotic liquid handling systems (for up to 96 samples in parallel). The unique design of the PhyTip® affinity columns allows bidirectional flow of the sample through the column to maximize the use of the resi…

Previously known as SPE-DEX ® 3100

Previously known as SolventTrapOG Automated Solvent Recovery System

Previously known as SPE-DEX ® 5000

The Biotage Isolera™ LS development-scale flash purification system dramatically shortens large-scale purification run-times with flow rates of 50-500 mL/minute. Simply select or create a method, load your sample, and run – it’s that easy. New advanced features include: the ability to collect fractions on two separate wavelengths, use of up to four solvents in a single gradient and add a third isocratic co-solvent.

Previously known as DryVap ® Automated In-Line Drying and Concentration System  

Ultravap™ Mistral Fully Robot Compatible Blowdown Evaporator

Spray particle and spray droplet size measurement