Drug discovery > Lead Discovery Products & Reviews

If you are involved in the analysis of fragrances, aromas, off-odours and other volatile organic compounds you may well wish that you could target trace componants at the low ppb level. You may also want to work with larger samples, than the 10-20 ml samples that conventional headspace analysis permits. The Entech 7150 Concentrator can be used to trap and focus headspace and air samples up to 1 litre in volume and to inject th…

The TRIDION™-9 is the world's smallest person-portable GC-TMS, which is fast, reliable, and easy to use. The integrated system features a low thermal mass capillary gas chromatograph with high-speed temperature programming and a miniaturized toroidal ion trap mass spectrometer with a mass range from 50 to 500 Daltons. Samples are injected using a novel CUSTODION® solid phase microextraction (SPME) fiber syringe. The entire TRI…

The 8000M Mixer/Mill® is a high-energy ball mill that accommodates sample sizes ranging from 0.2 - 10 grams. Ideal for grinding dry, brittle samples. Grinding and mixing vials are available in: hardened steel, stainless steel, tungsten carbide, alumina ceramic, zirconia ceramic, silicon nitride, agate, polystyrene, methacrylate, and polycarbonate. Applications include: Mechanical alloying, slurry grinding, blending powd…

High-performance MALDI-TOF/TOF mass spectrometer with a unique combination of speed, sensitivity, and accuracy, providing advanced analytical capabilities for research, discovery, and routine applications.

Compact Gas Flowmeter for use with GC

Automated PCR System

Automates sample preparation in preparation for amplification and detection Automates the sample preparation steps of real-time polymerase chain reaction (PCR) testing for analysis on the COBAS® TaqMan® Analyzers. This instrument operates with robotic precision to dramatically reduce hands-on time and enhance user productivity. It can be used for diagnostic applications and for screening pools of blood donations in clinical la…

CoulArray® - The Only Coulometric Array Detector for HPLC ESA's pioneering electrochemical technology has made possible the multi-sensor detector for HPLC. Measure multiple analytes simultaneously, including those that are chromatographically unresolved. Only ESA's unique coulometric array detection provides: Sensitivity to femtomole levels 3D resolution of co-eluting peaks Qualitative characterization of peaks Simpl…

The NEW Finnigan TSQ Quantum Discovery MAX: Extraordinary Value The high-performance, ultra compact benchtop Finnigan TSQ Quantum Discovery MAX incorporates innovative new technology for increased sensitivity, precision, ruggedness, and reliability. It is principally designed for high-productivity environments such as environmental, clinical and drug discovery laboratories. With the Ion Max source, the Finnigan TSQ Quantum Di…

A distinctive, lightweight, portable 2D and linear barcode reader, the VisionMate One Wireless reader employs Bluetooth® wireless technology.  Ideal for satellite locations or fieldwork, this versatile single tube reader provides secure data transmission between the reader and a computer or PDA, and is compatible with virtually any database.  The VisionMate One Wireless has a range of 100 meters (longer than a football field…

The miVac DNA is an ideal small concentrator for the molecular biology laboratory. A centrifugal concentrator capable of removing water and organic solvents from a variety of sample formats including tubes, microplates and vials. Making it an ideal "work-horse" concentrator for the busy lab. The built-in special runs for working with water and water mixtures improve performance and optimise concentration time and make the m…

Not treated (or medium binding) polystyrene surface is hydrophobic in nature and binds biomolecules through passive interactions Is suitable primarily for the immobilization of large molecules, such as antibodies, that have large hydrophobic regions that can interact with the surface Binding capacity of approximately 250 ng of mouse IgG/cm2 EIA/RIA plates are tested on lot-to-lot basis and the certification results for ea…

Three kits to cover a wide range of cAMP concentrations.After the introduction of IP-One, the first HTS immunoassay that can easily detect inositol(1)phosphate (IP1), a stable second messenger which tightly correlates with Gq-coupled receptor activity, the optimization of cAMP assays with the new HTRF® acceptor d2 offers a complete GPCR platform.The upgraded cAMP dynamic 2 and cAMP femto 2 assays, along with the new cAMP HiRa…

CompacT SelecT SC cultures multiple stem cell lines in parallel in T-Flasks and plates without cross contamination. Offers reliable and consistent maintenance, expansion and differentiation of stem cell lines. CompacT SelecT™ is the leading automated cell culture system, used in labs across commercial and academic life science. It is now available with new options to enable the culturing of complex cell lines for oncology pro…

Imagine preparing assay plates for siRNA screening, compound screening with biochemical and cell-based assays, PCR reactions and more all on a single liquid handling platform, with no tips and no cross-contamination. Labcyte has developed new acoustic droplet ejection (ADE) parameters that deliver built-in intelligence to enable users to transfer many different fluid types from a single instrument. All Echo systems come pre-ca…

Berghof 'speedwave® four' microwave digestion system - uncomplicated and straight forward digestions. Speedwave makes laboratory work easier and safer. Very easy handling thanks to the top loading concept. The entire, heavy rotor no longer needs to be lifted and placed in the microwave oven. It remains in the oven chamber and the vessels are simply inserted individually and removed again after digestion. The heated vessels…

96-well filter plate designed and optimized for aqueous solubility assaysDetermining a compound's aqueous solubility has become an essential early measurement to make in the drug discovery process. Poor water solubility can cause problems in many different in vitro testing techniques leading to unreliable results and/or reproducibility problems; insoluble precipitates have been shown to cause false positives in bioassays poten…

The Finnigan Surveyor Plus family of HPLC instruments is specifically optimized for the most demanding HPLC and LC/MS applications. Short cycle times, high sample capacity, low flow rate performance, and patented LightPipeTM technology have been integrated into one complete system for high-throughput sample processing environments.

Corning® Special Optics 96-well Microplates have black walls with ultra thin, clear bottoms for sharp, clear images and minimal background in fluorescent assays Designed to reduce well-to-well crosstalk during fluorescent assays Can be used for both top and bottom reading instrument Not treated (or medium binding) polystyrene surface is hydrophobic in nature and binds biomolecules through passive interactions Is suitable…

Echo® 555 liquid handler - the world's fastest acoustic dispensing platform for life science applications. The Echo® 555 liquid handler is the world’s fastest acoustic liquid handling platform for life science applications. Laboratories that demand very high throughput rely upon the Echo 555 liquid handler for round-the-clock trouble-free operation to enable the fastest discovery.The Echo 555 doubles the throughput of the Ech…

Echo®  qualified source plates are required for reliable dispensing with Echo® liquid handlers. These plates have been designed and tested for optimal performance in ADE and our software has been developed to ensure the reliable dispensing with these plates. Labcyte researchers have more than 100 years of combined experience in acoustic physics and have applied this unique and diverse knowledge to development of these source p…

Thermo Scientific ABgene 96-well Microtiter Plates are manufactured and in a class 100,000 clean room environment to ensure that each plate is contamination free. Plates are made using virgin medical grade polypropylene and have highly polished surfaces making them low binding and chemically resistant. Rigid side walls and industry standard footprint make plates suitable for automation and robotic handling, as well as for low…

Flat bottoms with 360 µL total volume Recommended working volumes of 75 to 200 µL Treated for optimal cell attachment Nonreversible low evaporation lids with condensation rings to reduce contamination Sterilized by gamma radiation and nonpyrogenic Individual alphanumeric codes for well identification Individually wrapped

Next-generation, liquid nitrogen-cooled, controllerless camera for spectroscopy. PyLoN®, a new line of controllerless, cryogenically cooled CCD cameras designed for quantitative spectroscopy applications that demand the highest possible sensitivity. In creating the new PyLoN platform, Princeton Instruments redesigned its industry-leading Spec-10 family of cameras to remove the external controller, increasing experimental flexi…