Drug discovery > Lead Discovery Products & Reviews

Build Crystallization Screens with Ease The FORMULATOR ® - Screen Builder is a next-generation liquid handler specifically designed for Protein Crystallography that uses patented microfluidic technology to dispense up to 34 different ingredients to design even the most complex optimization screens. A 96-nozzle dispensing chip can dispense any volume of any ingredient of any viscosity into any well.

The TEMPEST ®  is a high throughput, multiple reagent dispensing platform. With up-to 96 independently controllable dispensing nozzles it can be a plate-filling workhorse or a flexible assay-development partner, adapting to your needs on the fly. Used in a broad range of application areas such as cell-based and biochemical assays; molecular biology and NGS; as well as high-throughput screening.

Genizer Jacketed Liposome Extruder

The Genizer Online Extruder works with a high-pressure homogenizer to reduce the number of passes needed for optimal liposome size distribution and desired particle sizes. The homogenizer's diamond interaction chamber pre-treats the liposome sample to the nanoscale.

The NucleoCounter® NC-200™ is a high precision automated cell counter utilizing state-of-the-art image cytometry. With user-adaptable protocols and specialized assays for counting a wide range of mammalian cells, including adipose-derived stem cells, T cells, aggregated cells and cells on microcarriers, the NucleoCounter® NC-200™ provides an all-in-one solution for cell counting and cell viability determinations.

Robust methylation profiling microarray with unparalleled coverage of CpG islands, genes, and enhancers. Use for epigenome-wide association studies.

The NucleoCounter® NC-202™ automated cell counter is our 3rd generation cassette-based image cytometer. Featuring improved hardware and new NC-View™ software, we take precision, speed and data management to new levels.

The Via2-Cassette™ is our unique cell sampling device, eliminating human error by combining cell sampling, staining and loading into a single press on a piston. Individually volume-calibrated, it guarantees the highest precision in cell counting. The Via2-Cassette™ is a disposable plastic unit containing the fluorescent dyes used for analysis to ensure user safety and operational ease.

NucleoCounter® instruments provide platforms for determination of viability and cell count as well as advanced image analysis of yeast, veterinary semen, insect cells and mammalian cells, both primary cells and cell cultures, including cells in aggregate or microcarrier cultures.

The XcytoMatic® 40 (XM40™) is a high-throughput cell density and viability analyzer that can run 24 samples in under 14 minutes. The variation between cell counts for these samples is under 3%. If scale-out and scale-up is a concern, you can trust each XM40™ instrument in your production to deliver the same quality results.

“Allround“ SEC-columns for initial analysis of unknown samples

EcoSEC Elite and EcoSEC HT GPC/SEC Systems enable efficient polymer characterization

TSKgel GPC columns for organic-soluble polymers are packed with spherical particles composed of polystyrene crosslinked with divinylbenzene (PS-DVB)

Ca++Pure-HA is a hydroxyapatite resin used in the chromatographic separation of biomolecules.

TSKgel FcR-IIIA-NPR  affinity columns for direct analysis of mAb activity.

TSKgel Protein A-5PW affinity columns for direct analysis of mAb titer. 

TOYOPEARL NH2-750F offers a high binding capacity across a range of pH values and conductivities

TSKgel SuperQ-5PW is especially suited for industrial purification of oligonucleotides

TSKgel Butyl-NPR hydrophobic interaction columns for analysis of antibody-drug conjugates (ADCs) and as an orthogonal method to analyze protein aggregation, oxidation and deamidations.

The TSKgel DNA-NPR weak anion exchange column is designed to analyze nucleic acids. It routinely separates plasmid isoforms, PCR products and oligonucleotides.

BellBrook Labs delivers bespoke assay development and lead discovery solutions using its Transcreener® HTS platforms. Their expert team optimizes detection of small-molecule modulators for enzyme targets—tailoring buffer, enzyme, and detection conditions to yield strong initial-velocity signals (Z’ 0.7–0.9) in just 2–4 weeks.

The Transcreener® ADP² Kinase Assay Kit universally detects ADP produced by any kinase or ATPase using a direct mix‑and‑read format, eliminating coupling steps. Available in FP, FI, and TR‑FRET formats with far‑red tracers to minimize interference, it's HTS-ready across 96‑, 384‑, and 1536‑well plates with robust Z' ≥ 0.7 performance.

The Transcreener® AMP²/GMP² Phosphodiesterase Assay Kit directly detects AMP or GMP produced by PDEs, ligases, synthetases, ENPP1, and related enzymes using a mix‑and‑read FP or TR‑FRET format—no coupling steps needed. Compatible with 1–1000 µM native substrates, it delivers excellent HTS performance (Z’ ≥ 0.7, ≥100 mP shift) in a one-step, far‑red fluorescence assay.

Meet Absorbance One, the UV/VIS spectrophotometer, that's bespoke to your assay! The Absorbance One brings world-class specifications to the palm of your hand. Disrupting the idea of centralized equipment, the Absorbance One’s minimal footprint and low price point mean it is available to every lab - and even every workstation. Designed for specific applications, the Absorbance One is your decentralized UV-visible spectrophoto…

Luminescence 96 is a groundbreaking luminometer that sets a new standard in measurement technology, featuring an impressive array of 96 individual detectors. Its sleek and space-saving design, coupled with an incredibly affordable price, revolutionizes access to Luminescence-based assays, making it an essential addition for laboratories worldwide.