Drug Discovery & Development Products & Reviews

Gyrolab® Assay Toolbox with 1000 nL sample volume for development of HCP assays with the components of ready-to-use HCP Kits.

The Gyrolab® AAV9 Titer Kit determines AAV9 titer in samples from process development and in the manufacturing of AAV9 viral vectors

Gyrolab huIgG Kit – Low Titer is a ready-to-use Gyrolab kit for determination of human monoclonal antibody (mAb) titers up to 20 µg/mL.

The next generation PurePep ® Sonata ® + provides uncompromising productivity using real-time flow technology and new intuitive software.

Gyrolab® Assay Toolbox with 4000 nL sample volume for development of HCP assays with the components of ready-to-use HCP Kits.

The Gyrolab® Human IL-10 Kit Reagents enables rapid quantification of IL-10 in human serum samples

The Gyrolab® Human IL-4 Kit Reagents enables rapid quantification of IL-4 in human or cyno serum samples

The Gyrolab® Human IL-6 Kit Reagents enables rapid quantification of IL-6 in human or cyno serum samples

The Gyrolab® Human IFN-gamma Kit Reagents enables rapid quantification of IFN-gamma in human or cyno serum samples

Gyrolab® Generic Cyno ADA Kit Reagents enable detection of anti-drug antibodies of human IgG or Fab in cynomolgus monkey matrix.

The Gyrolab® 2G Generic PK Kit enables high sensitivity quantitation of intact human IgG (IgG1, IgG2, IgG4 subtypes) in preclinical matrices

Peptide under GMP standard, available for both API and neoantigen peptide

Custom peptide service with more than 300 modification choices

GenScript’s Neoantigen Peptide Synthesis Service supports everything from functional screening of neoantigen candidates for TCR therapy to clinical stage vaccine immunogenicity testing.

YMC HT Glass Columns are specially designed to accommodate the stringent requirements of high-temperature liquid chromatography applications. Capable of performing efficiently at temperatures up to 70 °C, these columns are perfectly suited for a broad spectrum of purification tasks, particularly in biochemical liquid chromatography (BioLC), where high temperatures are pivotal.

From laboratory to pilot scale, YMC offers reliable, high quality glass columns for all kind of application areas.

YMC PilotPLUS columns are completely biocompatible and characterised by safe and easy handling.

Does your application require customised pilot columns? With YMC Pilot columns, customised versions can be constructed to address your needs. Of course standard dimensions are available, too!

Stop gambling on cycle numbers. The icon96 uses iconPCR™ technology with AutoNorm™ software to provide real-time fluorescence feedback in each of 96 independent wells, preventing under-amplification dropouts and over-amplification artifacts—delivering balanced, sequencing-ready libraries without manual quantification or normalization.

High-throughput boosting. Compatible with manual workflows and liquid handlers.

Our Metabolite Identification service for peptides utilizes HRMS to characterize peptide metabolism (e.g., hydrolysis, oxidation, glucuronidation). The assay identifies and semi-quantifies metabolites in plasma/tissues, enabling ADME profiling (clearance, bioavailability), toxicity screening (reactive metabolites) and peptide optimization (PK/PD enhancement). Integrated with preclinical data, it supports metabolically stable p…

Our Comprehensive In Vitro Proarrhythmia Assay (CiPA) service assesses proarrhythmic potential of compounds beyond hERG inhibition, integrating effects on multiple cardiac ion channels and human iPSC-derived cardiomyocytes via patch clamp and multi-well MEA platforms. Aligned with FDA's CiPA initiative and ICH E14/S7B guidelines, it predicts QT prolongation and TdP risks for enhanced specificity in early drug safety evaluation…

Our Protein Binding Platform assesses drug-protein interactions using equilibrium dialysis and ultracentrifugation methods to determine unbound fractions and distribution in biological samples including plasma, blood, tissues, and cells. This essential ADME service evaluates reversible drug transfer between compartments, providing insights into pharmacokinetics, bioavailability, and potential interactions.

Our hERG Safety Screening service employs the Synchropatch-384 automated patch clamp system to assess compound effects on the hERG potassium channel. This high-throughput assay detects inhibitors that may prolong QT intervals and cause arrhythmias, aiding early drug safety evaluation. With precise data under physiological conditions, it supports regulatory compliance to advance safer therapeutics. 

Our Metabolite Identification service employs HRMS /LC-MS/MS to decode degradation pathways of antisense oligonucleotides (ASOs), siRNAs, and modified variants, identifying chain-shortened metabolites (5’/3’ cleavage), phosphorothioate changes (desulfurization, inversion) and base/nucleotide alterations (deamination/depurination). Through plasma/tissue/cell analysis, we reveal metabolic stability, biodistribution, and exonucle…