Drug Discovery & Development Products & Reviews

Lynx Certified Disposable Tips are manufactured in GMP clean-room conditions, with gamma irradiation and in-line visual QA inspection, ensuring sterility and reliability. Packaged in ANSI-standard tip boxes, they integrate seamlessly across Lynx decks—making tip handling safe, flexible, and maintenance-free.

On the Fly, Swappable, Multipurpose Tools! The Multi-Core Pipetting Arm (MCPA), Lynx offers seamless core swapping, increased throughput, and ultimate flexibility — empowering labs to do more, faster.

Elephas Live™ Platform: Ex vivo cytokine profiling enables precision medicine

Plasmax™ is a physiologically relevant cell culture medium which closely mimics the nutritional & metabolic profile of human plasma, containing over 80 optimised components.

Syngeneic urothelial carcinoma model for bladder cancer research and immunotherapy development

KCGS is a comprehensive collection of 295 highly selective kinase inhibitors targeting 262 human kinases

Syngeneic pancreatic ductal adenocarcinoma (PDA) cell line from the KPC mouse model for immune-competent studies in drug discovery, biomarker development, genetic research, and metastasis

Our Metabolite Identification service for peptides utilizes HRMS to characterize peptide metabolism (e.g., hydrolysis, oxidation, glucuronidation). The assay identifies and semi-quantifies metabolites in plasma/tissues, enabling ADME profiling (clearance, bioavailability), toxicity screening (reactive metabolites) and peptide optimization (PK/PD enhancement). Integrated with preclinical data, it supports metabolically stable p…

Our Comprehensive In Vitro Proarrhythmia Assay (CiPA) service assesses proarrhythmic potential of compounds beyond hERG inhibition, integrating effects on multiple cardiac ion channels and human iPSC-derived cardiomyocytes via patch clamp and multi-well MEA platforms. Aligned with FDA's CiPA initiative and ICH E14/S7B guidelines, it predicts QT prolongation and TdP risks for enhanced specificity in early drug safety evaluation…

Our Protein Binding Platform assesses drug-protein interactions using equilibrium dialysis and ultracentrifugation methods to determine unbound fractions and distribution in biological samples including plasma, blood, tissues, and cells. This essential ADME service evaluates reversible drug transfer between compartments, providing insights into pharmacokinetics, bioavailability, and potential interactions.

Our hERG Safety Screening service employs the Synchropatch-384 automated patch clamp system to assess compound effects on the hERG potassium channel. This high-throughput assay detects inhibitors that may prolong QT intervals and cause arrhythmias, aiding early drug safety evaluation. With precise data under physiological conditions, it supports regulatory compliance to advance safer therapeutics. 

Our Metabolite Identification service employs HRMS /LC-MS/MS to decode degradation pathways of antisense oligonucleotides (ASOs), siRNAs, and modified variants, identifying chain-shortened metabolites (5’/3’ cleavage), phosphorothioate changes (desulfurization, inversion) and base/nucleotide alterations (deamination/depurination). Through plasma/tissue/cell analysis, we reveal metabolic stability, biodistribution, and exonucle…

Our Metabolite Identification service for Antibody-Drug Conjugates (ADCs) applies immuno-capture and HRMS to detect payload-containing catabolites, linker cleavages, and biotransformations in biological samples. This targeted assay quantifies free payloads, metabolites, and intact conjugates, assessing stability and off-target risks. Essential for ADC development, it informs payload design and pharmacokinetics, ensuring compli…

Our Cassette and Discrete PK Study service evaluates pharmacokinetic profiles of small molecules in key preclinical species: rat, mouse, dog, and monkey. It uses cassette dosing for high-throughput screening of multiple compounds simultaneously and discrete dosing for precise individual assessments for ADME parameters. This aids in early drug optimization, predicting human PK, and ensuring regulatory compliance for safer candi…

More than ten years of synthesis experience working with both life sciences and specialty chemicals companies enable Alfa Chemistry to complete any challenging custom synthesis project from milligram to kilogram scale. We will safeguard your confidentiality, as our clients retain all intellectual property of their research.

Alfa Chemistry has been providing custom synthesis services for building blocks to customers worldwide. Our featured products include mainly pyridines, boric acids, miscellaneous and chiral molecules.

Clear, colorless viscous liquid, BioReagent, suitable for cell culture & biochemistry, ≥95.8%

Alfa Chemistry provides Karl Fischer (KF) moisture testing services using both volumetric and coulometric titration systems for accurate water content determination in solids, liquids, and gases. The service supports trace-level moisture analysis, quality control, stability studies, and regulatory compliance across pharmaceutical, chemical, food, and advanced material applications.

Alfa Chemistry provides high-quality oligonucleotide series products including synthesis building blocks and cyclic dinucleotides.

Alfa Chemistry’s Potency Testing Services provide accurate determination of active ingredient concentration in compounded medications. Using advanced chromatographic and spectrophotometric techniques, our cGMP-compliant laboratory ensures the safety, efficacy, and regulatory compliance of pharmaceutical preparations across diverse dosage forms, including powders, capsules, tablets, creams, suspensions, and more.

We offer a wide range of high-quality Active Pharmaceutical Ingredients (APIs) to support pharmaceutical research and drug development across multiple therapeutic areas, including oncology, cardiology, neurology, respiratory, immune, and metabolic diseases. All APIs are developed under strict quality control to meet international standards. You can browse our product list or find the product you want through the search box.

Alfa Chemistry’s Stability Testing Services provide comprehensive evaluation of product quality over its shelf life. Using advanced analytical techniques and state-of-the-art instrumentation, we assess the physical, chemical, and functional stability of foods, OTC drugs, dietary supplements, toiletries, and cosmetic products to ensure safety, efficacy, and compliance with regulatory standards.

Alfa Chemistry’s Pharmaceutical Analytical Services offer expert testing and characterization throughout drug development and production. Using a cGMP-compliant laboratory and advanced analytical techniques, we provide biopharmaceutical characterization, impurity profiling, stability assessment, and formulation analysis to ensure product safety, efficacy, and regulatory compliance.

Alfa Chemistry provides synthetic peptides with a wide range of labels, scales, purities and delivery time options to meet your research needs. We ensures that each custom peptide is triple checked for quality via both mass spectrometry(MS) and high performance liquid chromatography (HPLC) analyses after each step during peptide purification and quality control (QC) procedures.

Automated Cell Density/Cell Viability Analyzer and Cell Counter