Drug discovery > Basic Research Products & Reviews

Enables sequencing of genes that are difficult or impossible to fully sequence with short read technology. 

Focus on important genes in pharmacogenomics that are critical to drug metabolism and patient therapeutic response.

Twist Diversity SNP Panel gives researchers a new flexible ethnicity-neutral gold standard to use for GBS

Deep coverage of clinically focused targets that allow for the study of methylation patterns that may be relevant to early cancer detection and diagnosis from tumor and liquid biopsy samples.

Streamline the identification of heritable disease-linked alleles, be it through carrier screening or pre- and post-natal testing.

The Twist Alliance Clinical Research Exome helps support the Broad Institute Genomics Platform and was designed using validated data from clinical patient samples.

The Twist Alliance Canine Exome developed in collaboration with the Broad Institute

The Twist Alliance CNTG Exome - 41 MB provides highly uniform coverage of the entire exome as well as full coverage of the mitochondrial genome.

Coverage of rare disease-associated genes 

Coverage of 72 selected cancer-associated genes

The Twist Respiratory Virus Research Panel enables comprehensive detection and sequencing of 29 common respiratory viruses, allowing researchers to identify pathogens and analyze their genomes.

Fast and Easy Library Workflows

Twist's RNA Sequencing Solutions provide comprehensive next-generation sequencing (NGS) workflows, offering both targeted and whole transcriptome approaches to generate uniform, high-quality RNA sequencing libraries from diverse sample types.

The Twist RNA Exome offers a comprehensive solution for capturing human protein-coding regions, enabling efficient transcriptome analysis, isoform study, and fusion detection with high sensitivity and specificity.

The Twist NGS Methylation Detection System provides a robust, end-to-end sample preparation solution for identifying methylated regions in the human genome. The workflow employs a unique enzymatic process from New England Biolabs® that is much less damaging to DNA, alongside Twist‘s Custom Methylation Panel design.

The Twist Bioscience MRD Rapid 500 Panel is a scalable target enrichment solution for monitoring minimal residual disease that leverages Twist’s silicon based DNA synthesis platform to design and manufacture capture panels for personalized medicine. 

The Twist UMI Adapter System enhances the detection of low-frequency somatic variants in cell-free DNA (cfDNA) by incorporating unique molecular identifiers (UMIs) during library preparation, increasing sensitivity and reducing PCR errors.

Twist's cfDNA Pan-Cancer Reference Standard v2 provides researchers with high-quality, synthetic reference materials to assess and validate liquid biopsy assays, enhancing the detection of low-frequency cancer associated variants.

High Sensitivity. High Conversion. Low-Input

Twist’s RNA sequencing workflows offer a complete NGS solution that produces uniform libraries for RNA sequencing.

Maintain sample identity throughout the workflow  

Reveal the molecular signatures of tumor immune responses

Conjugate IgG antibodies with your choice of up to 10 metals, with each kit containing enough material to conjugate 40 antibodies in 100 µg amounts.  

Targeted NGS library preparation, gene expression and genotyping. Increase productivity and efficiency with automated, cost-effective, and easy-to-use workflows for targeted DNA next-generation sequencing (NGS) library preparation, gene expression analysis and genotyping by allele-specific PCR.

Automated platform for single-cell omics and multi-omic research using solid-state microfluidics. C1 with integrated fluidic circuits (IFCs) enables the preparation of single-cell templates for total RNA sequencing and multi-omic applications such as preparing mRNA and DNA and mRNA and protein from the same isolated and imaged single cell.