Drug discovery > Basic Research Products & Reviews

Agilent’s Human ENCODE ChIP-on-chip microarray is designed to identify human DNA binding proteins within the ENCODE regions. The microarray is designed to target ENCODE regions with more than 53,000 validated probes, which are proven to deliver robust hybridization and optimal binding critical to reliable data.

Agilent SureSelect All Exon kits are the most widely used target enrichment solution for exome sequencing. SureSelect Human All Exon V5 (targeting coding regions only) and V5+UTRs (targeting coding regions plus UTRs) have been updated to provide the greatest sequencing efficiency and enable samples ready for sequencing the next day. Greater coverage with less sequencing for lower overall costs – up to 60% less sequencing than…

Agilent Deconvolution Reporting Software (DRS) for GC/MS is an application for target compound analyses that combines results from the Agilent MSD Productivity ChemStation, the NIST Automated Mass Spectral Deconvolution and Identification Software (AMDIS), and the NIST 2008 Mass Spectral Search Program (NIST08) into one easy-to-read report. 

Agilent Solutions for Automated NGS Sample Prep provide: Flexibility to automate virtually any NGS reagent Performance to dramatically increase throughput and walk-away time Optimized SureSelectXT protocols to rapidly automate your NGS Sample Prep Agilent NGS Option A and Option B Both Deliver Higher Throughput with Less Hands-On Time Automating your NGS sample preparation with either Agilent NGS Option A or Option B…

SurePrint G3 Gene Expression Microarrays offer a comprehensive coverage of genes and transcripts. Superior sensitivity with a wide dynamic range of over 5 orders of magnitude ensures detection of low and high expressors for the most biologically relevant data. With the newest Gene Expression v2 Microarray, new large intergenic non-coding RNA (lincRNA) probes designed to the human catalog of lincRNAs from the Broad Institute al…

The pDual and pDual GC expression vectors are designed for high-level expression of heterologous genes in both eukaryotic and prokaryotic systems.High-level protein expression in bacterial or mammalian systems Saves time by eliminating the need to subclone Express protein as a native or tagged fusion protein Epitope tagged for simple detection and affinity purification Clone seamlessly without compatible restriction sites Avai…

Herculase II Fusion DNA Polymerases Pfu Ultra DNA Polymerases & PCR Master Mixes PfuUltra II Hotstart DNA Polymerases & PCR Master MixesHerculase II Fusion DNA PolymerasesThe Herculase II fusion DNA polymerase produces superior yields with extension times as short as 15 sec/kb (see Figure), even with genomic DNA targets up to 12kb. Herculase II fusion DNA polymerase helps overcome PCR challenges with successful amplification o…

The SureSelect Strand-Specific RNA Library Preparation kit prepares Poly(A) enriched libraries for whole-transcriptome sequencing. Sequence a wide range of RNA to detect gene expression changes and alternative splicing. The kit contains mRNA sequencing library preparation and enrichment materials.

Genomic DNA ScreenTape analysis provides fast, automated and reliable electrophoretic separation of input genomic DNA samples. The gDNA ScreenTape assay can separate DNA samples from 200 to more than 60,000 base pairs in less than 2 minutes/sample. Samples can be analyzed from multiple sources including FFPE.

The praying mantis diffuse reflectance accessory is useful for measuring the diffuse reflectance of low volumes of powders and pastes. Using two large hemispherical mirrors, it collects the light reflected from the crystalline sample, enabling the full wavelength range of the Cary instrument to be used. The accessory can be used with the Cary 4000, 5000, 6000i, and 7000 instruments.

Learn about our extensive range of CGH + SNP microarrays dedicated to cytogenetic workflows. We provide whole genome CMA at variable resolutions, down to exon level, CGH+SNP arrays to analyze CN and LOH in a single experiment and application specific designs, including pre- post-natal, PGS, CNV and Cancer specific microarrays. Agilent’s CGH platform provides unmatched flexibility on content and throughput, thanks to eight diff…

The Agilent Cary 7000 universal measurement spectrophotometer (UMS) will satisfy all your solid sampling needs. Collect hundreds of UV-Vis-NIR spectra overnight, or characterize optical components or thin films in minutes to hours rather than hours to days. The Cary 7000 UMS is a turn-key solution for research, development, and QA/QC in optics, thin films/coatings, solar, and glass.

The HaloPlex Cancer Research Panel enables fast, simple, and efficient analysis of genomic regions of interest for cancer research for a large number of sample types, including FFPE. HaloPlex Cancer is uniquely suited to high performance with cancer research samples, which are commonly preserved as formalin fixed and paraffin embedded (FFPE). This FFPE process often results in highly fragmented DNA, resulting in insufficient…

Agilent’s GeneSpring NGS software suite includes data analysis workflows for Methyl-Seq, RNA-Seq, DNA-Seq, Chip-Seq and Small RNA-Seq data. GeneSpring NGS provides SureSelect customers with an easy to use QC, visualization and reporting tool for Methyl-Seq, RNA-Seq and DNA-Seq applications. GeneSpring NGS also allows the detection of transcriptomic changes like splice variants and gene fusions, or identify structural variation…

HaloPlex technology provides outstanding performance, streamlined workflow, and low sample input requirements for next generation sequencing of human exomes. The HaloPlex Exome has been optimized to provide comprehensive coverage of the coding regions of the human genome with minimal hands on time and requires only 200ng of input DNA. The Haloplex Exome performance and workflow is ideal for clinical research: • Outstanding cov…

Agilent SureSelectXT Human Methyl-Seq is the first comprehensive target enrichment system to enable researchers to focus on the regions where methylation is known to impact gene regulation. It targets the most complete Methyl-Seq content, including cancer tissue-specific DMRs, GENCODE promoters, CpG islands, shores and shelves ±4kb, DNaseI hypersensitive sites and RefGenes. • Delivers more information than methylation microarr…

Agilent Haloplex custom kits offer the flexibility to create custom panels for any genomic regions of interest. A unique and efficient library prep-free workflow enables complete target enrichment in less than 6 hours from just 200 ng of input DNA.

Agilent HaloPlex panels are predefined designs which focus on targeted gene sets for specific applications. Agilent offers two catalog HaloPlex panels, the Cancer Research Panel and the Cardiomyopathy panel.The HaloPlex Cardiomyopathy (catalog) is a next generation sequencing target enrichment panel designed specifically for inherited forms of cardiomyopathy. Following a careful review of cardiomyopathy publications as well as…

SureTag Labeling Kits provide all necessary reagents for efficient sample fragmentation, enzymatic labeling and clean-up. The SureTag DNA Labeling Kits generate robust cyanine-labeled genomic DNA targets for optimal hybridization signals with high signal-to-noise ratio and low probe-to-probe variability.

HER2 IQFISH pharmDx™ is a direct fluorescence in situ hybridization (FISH) assay based on Dako's new fast IQISH hybridization buffer chemistry. The new IQISH hybridization buffer is non-toxic and allows genomic DNA probe hybridization to be performed in just 60-120 minutes. The short hybridization time results in a turnaround time of about 3½ hours for a complete FISH staining from deparaffinization to mounting. HER2 IQFISH p…

TOP2A IQFISH pharmDx™ is a direct fluorescence in situ hybridization (FISH) assay based on Dako's new fast IQISH hybridization buffer chemistry. The new IQISH hybridization buffer is non-toxic and allows genomic DNA probe hybridization to be performed in just 60-120 minutes. The short hybridization time results in a turnaround time of about 3½ hours for a complete FISH staining from deparaffinization to mounting. TOP2A IQFISH…

The SureSelect Focused Exome is a highly targeted design that enables analysis of only disease-associated targets, enabling superior coverage of disease-associated regions even on benchtop sequencers. This design provides 20 or more reads for 95% of targets at 1.5Gb (100x) of sequencing and 98% of targets with 3Gb (200x) of sequencing.

An electronic transwell device for quantitative kinetic analysis of cell invasion/migration.

Perform truly comprehensive mycotoxin screening applications with the Mycotoxins and Related Metabolites Personal Compound Database and Library (PCDL) for TOF and Q-TOF LC/MS systems. Detailed acquisition method setup information allows fast ramp-up to full productivity.

The Pesticide Personal Compound Database and Library (PCDL) for TOF or Q-TOF LC/MS systems contains a curated accurate-mass database with over 1,700 compounds and accurate-mass MS/MS spectra for more than 800 compounds. Detailed acquisition method setup information allows fast ramp-up to full productivity.