Merck Products & Reviews

Highly characterized, cryopreserved human colon intestinal organoids derived from integration-free human induced pluripotent stem cells (iPSCs).

The 3dGRO™ Human Lung Organoid Culture System is a multi-stage culture system for efficient differentiation of human induced pluripotent stem (iPS) cells to mature lung organoids.

ECMatrix™ laminin substrates for culturing pluripotent stem cells (iPSCs) to promote in vivo–like morphology and simulate a more physiologically relevant environment for better intercellular interactions and better predictive cell models.

Decellularized extracellular matrix (dECM) hydrogels for 2D and 3D cell culture applications.

Ready-to-use, 96-well black-walled glass-bottom microplates containing precast synthetic hydrogels designed to easily establish 3D cell cultures by direct seeding of cells.

Fluorescent dyes, probes, and biosensors for live cell imaging.

Validated, ethically-sourced human primary and stem cells from industry-leading manufacturer PromoCell ® . 

Supel™ BioSPME 96-Pin Devices were developed to greatly improve upon the speed and simplicity plasma protein binding studies and other free analyte analyses.  Our technology offers a 3x faster workflow compared to rapid equilibrium dialysis based methods, is amenable to both automation and manual operation, and is a convenient universal 96-pin format compatible with standard 96-well consumables.  

Inexpensive portable devices and test kits for quantitative on-the-spot analysis with easy handling with the precision of instrumental analysis

Save time and get quick and reliable results in food, water and environmental analysis procedures

Get instant high-quality results in environmental analysis and industrial-in-process controls

Analyze your MQuant® test strips with your smartphone for fast, convenient, and precise results

Volumetric Solutions for Precise Titration Results

Safeguard the high quality of our volumetric reagents

Primer and probe pools for the U.S. CDC and and Charité tests.

Sigma-Aldrich ® one-part sgRNA and two-part crRNA:tracrRNA systems accelerate genome editing with Cas9 protein, mRNA, or established Cas9 expressing cell lines. Our guides are compatible with a variety of delivery methods including microinjection, electroporation, and lipofection.

With the largest portfolio of Cas9 proteins available, Merck make it easy to find the perfect nuclease for your gene editing experiment.

Merck's immuno-oncology cell lines are innovative research tools for biologics discovery and clinical development. These are the perfect cell-based assay tools you need for the entire drug discovery and clinical development process. Whether you need screening tools for CAR/TCR therapies and mAB development, target cells for efficacy testing, or potency assays for clinical development, Merck provides functional biologically-re…

The largest and most validated shRNA collection from the RNAi consortium (TRC). Merck's unique shRNA formats leverage the discovery potential of the trusted and proven TRC shRNA collection. When you partner with them, you gain access to their world class lentiviral production expertise and the formats and specifications for RNAi knockdown experiments at any scale.

A comprehensive biobank of highly characterized tissue-derived human gastrointestinal organoids from normal and diseased patients.

Nuclease-independent applications of CRISPR provide equal targeting specificity but instead of cutting, CRISPRi allows for targeted interference of gene function by delivering transcriptional repressor domains to a specific target sequence using modified dCas9 + gRNA complexes. Gene knockdown is complementary to CRISPR-KO and CRISPRa (activation) and has distinct advantages over existing loss-of-function strategies like RNAi.…

Patient-derived organoids (PDOs) are novel in vitro 3D cell models that preserve original tissue physiology and molecular pathology.

MS β-glucuronidase is a prebuffered, bench-stable, and automation-ready hydrolysis mix for urine drug testing workflows. Discover how to leverage its reduced hands-on time and improved stability. 

The next generation of RNP reagents

SeQuant ® HILIC (hydrophilic interaction liquid chromatography) HPLC columns carry densely bonded, zwitterionic functional groups. These columns are available in a variety of lengths, particle sizes, and pore dimensions while showing an exceptional reproducibility and robustness.