PURedit™ CRISPR Synthetic sgRNA and Cas9 Protein
The next generation of RNP reagents

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It is now possible for your CRISPR experiments to have it all. Industry-leading specificity to reduce off-target effects without a decrease in on-target cutting efficiency. Ribonucleoprotein complexes (RNPs) are the gold standard for CRISPR experiments. The Sigma-Aldrich® gene editing portfolio now offers PURedit™ synthetic sgRNAs and PURedit™ Cas9 protein, engineered to meet superior manufacturing standards, tailored for pre-clinical research.
• Superior manufacturing standards ensuring high quality and consistency
• Guaranteed to edit – pre-designed and custom sequences
• Efficiency – high on-target editing without compromising specificity
• The highest activity in difficult-to-target loci
Brochures
Superior gene editing with PURedit™ RNPs
This product brochure describes the applications and advantages of Merck’s PURedit™ CRISPR reagents. Translational experiments require the highest efficiency to ensure your therapeutic is a success. Discover how PURedit™ RNPs are designed to accelerate genome editing with industry-leading on-target activity while maintaining low off-target editing, especially at target sites that are difficult to edit.
PURedit CRISPR Reagents
PURedit™ CRISPR products are engineered to tackle the most challenging gene editing projects. Download this application note to see the various applications in which PURedit™ Cas9, a novel high-fidelity, high-activity variant can be used
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