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xCELLigence RTCA HT-BioTek BioSpa8 – Screening Model by Agilent Technologies


Integration of the xCELLigence Real Time Cell Analyzer (RTCA) HT instrument with the BioTek BioSpa 8 automated incubator expands the screening throughput of your RTCA HT instrument to eight 384-well plates. Label-free high-throughput xCELLigence Real-Time Cell Analysis is ideal for screening viral mediated cytopathic effects (CPE), neutralizing antibodies, antibody-dependent cytotoxicity (ADCC), and compound mediated cytotoxicity.


xCELLigence RTCA HT-BioTek BioSpa8 – Screening Model by Agilent Technologies product image
xCELLigence RTCA HT-BioTek BioSpa8 – Screening Model
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xCELLigence Real-Time Cell Analysis uses impedance-based biosensors to obtain non-invasive, label-free measurements, continuously monitoring cell health, behavior, and function with high accuracy, sensitivity, and reproducibility. Integrating the BioSpa 8 Automated Incubator with the xCELLigence RTCA HT model enables live cell analysis of up to eight 384-well E-plates (a total of 3,072 wells) to meet high throughput sample screening needs.

Features:

  • The xCELLigence RTCA HT instrument with BioTek BioSpa 8 automated incubator enables live cell analysis up to eight 384-well E-plates (a total of 3,072 wells) with non-invasive and label-free real-time impedance technology.
  • Kinetic measurement of cell health, viability, or response to treatments with high sensitivity, accuracy, and reproducibility, provides a continuous flow of real-time data. The information gained from real-time live cell analysis goes far beyond end-point measurements.
  • Automated workflow allows users to simply add cells to E-Plates 384 and begin kinetic measurements at physiological conditions.  The BioSpa8 Robotic Arm transfers E-Plate 384 from the incubator to the xCELLigence RTCA HT Station. Multiple E-Plates 384 are processed while unattended, saving time in the lab.
  • Critical physiological conditions are controlled and maintained in the BioSpa8 incubator to ensure assay success. Temperature and CO2/O2 control, plus humidity monitoring in the BioSpa facilitate live cell processes, and the cradle of the RTCA HT unit is temperature-controlled, for minimal disruption of the cells. The software continuously records environmental conditions.
  • Small footprint saves benchtop space 
  • Set-up of the HT-BioSpa is completed same-day – start screening within hours
  • User-friendly RTCA software Pro HT-BioSpa enables simple assay setup (scheduling) for both single and multiple users, real-time data visualization, and powerful data analysis. 
  • Ideal for high throughput screening of therapeutic antibodies, drug compounds, and cytotoxicity.
  • Typical applications include Compound-mediated cytotoxicity assay; Viral-mediated cytopathic effect (CPE); Neutralizing antibody screening; Antiviral drug screening; Immune cell potency assay; Antibody-dependent cell-mediated cytotoxicity (ADCC) assays.

Product Overview

xCELLigence RTCA HT-BioTek BioSpa8 – Screening Model by Agilent Technologies product image

xCELLigence RTCA HT-BioTek BioSpa8 – Screening Model

Manufacturer Agilent Technologies

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