UP.SIGHT™ - Single Cell Dispenser and Plate Imager
The ultimate upgrade in cell line development.
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Essential instrument for monoclonal cells in HTS
Monoclonal cell culture
Axxam has revolutionized the limiting dilution process with the UP.SIGHT instrument over the past year. We experienced the power of this remarkable tool with its intuitive interface and double assurance of clonality, enabling us to accelerate the production of stable monoclonal cell lines expressing a diverse range of targets for our high-throughput screening campaigns. This invaluable asset has been an integral part of our cutting-edge research programs, ensuring our work remains at the forefront of scientific innovation.
Review Date: 17 Jul 2023 | CYTENA
Great advance in technology for our production platform
Strain development
Very gentle and reliable cell dispensing system that allows for automation of assuredly monoclonal cell line generation with our very large and fragile protoplasts. The UP.SIGHT is easy to handle and easy to integrate into the existing lab due to its small footprint.
Review Date: 11 Jul 2023 | CYTENA
The UP.SIGHT™ streamlines cell line development (CLD) workflows by automating labor-intensive and time-consuming steps. We have combined our patented, highly efficient, fast and gentle single-cell dispensing technology with a superfast, high-quality imaging system that provides a full well image without image stitching. The UP.SIGHT offers two independent methods of assuring monoclonality: first, images are taken at the dispensing nozzle to ensure only one cell is placed in each well and nonclonal droplets are discarded; second, the single cells are confirmed once more with 3D Full Well Imaging, a new and innovative method that images the full volume of each well from the point of dispensing using the integrated imager, leading to a probability of clonality >99.99%.
Key features and benefits:
- Double assured clonality
- Minimal cell loss
- Small footprint and benchtop
Relevant applications:
- Cell line development
- Single-cell cloning
- Monoclonal antibody development
