MiroSynth™ Cell Free DNA
Plasmid grade performance, without tradeoffs.
Receive your quote directly from the manufacturer.
Built Without Bacteria
By removing bacterial cloning from the process, MiroSynth™ helps simplify how DNA is sourced, built, and used across demanding applications. Ribbon Bio’s MiroSynth™ Cell-Free DNA delivers:
- Sequence-verified, linear DNA ready-to-use
- High complexities and accuracy
- No cloning, bacterial constraints, and workflow delays.
Engineered for Accuracy
MiroSynth™ Cell-Free DNA combines algorithm-driven design, enzymatic assembly, and NGS-based validation to produce highly accurate, full-length DNA molecules.
- ≥90% of sequence-correct molecules across constructs up to 12 kb.
- Accuracy is maintained across increasing sequence length and complexity.
Why choose MiroSynth™?
Ribbon Bio’s MiroSynth™ Cell-Free DNA delivers:
- Sequence-verified, linear DNA ready-to-use
- High complexities and accuracy
- No cloning, bacterial constraints, and workflow delays
For research use only. Not for use in diagnostic procedures.
One-shot protein engineering with Ribbon's MiroSynth DNA in a rapid and integrated cell-free workflow
This whitepaper presents a streamlined approach to protein engineering using a fully cell‑free workflow enabled by MiroSynth™ Cell‑Free DNA. By integrating computational design, high‑accuracy DNA synthesis, and multiplex protein expression screening, the method reduces the time and complexity of traditional design‑build‑test cycles. The workflow demonstrates how rapid, cell‑free DNA production and expression can improve protein stability, yield, and scalability, offering a faster route to optimized protein variants for biopharmaceutical and research applications.
Accelerating enzyme optimization through an integrated design-to-function workflow
Tuesday, December 2, at 15:00 GMT | 16:00 CET | 10:00 EST | 7:00 PST
Ready to supercharge enzyme discovery? Join leaders from Ribbon Bio, Scala Biodesign, and Nuclera for an exclusive webinar on building a fully connected “Design–Build–Test–Learn” pipeline that propels protein engineering to new speeds and reliability.
Using a DNA-binding enzyme as a case study, this session will showcase how AI-driven protein design, advanced synthetic DNA assembly, and rapid expression technologies can converge to accelerate the discovery and validation of functional enzyme variants. Our expert speakers will guide you through each stage of the workflow, from target identification and in silico optimization, to DNA synthesis, expression screening, and functional evaluation of improved variants.
Discover how this integrated, cross-platform workflow not only slashes R&D timelines but also boosts your confidence in selecting winning variants while de-risking enzyme development projects.
Key learning objectives:
- Discover how AI-driven design can generate targeted enzyme variants optimized for activity, stability, or specificity.
- Accelerate the build phase with high-accuracy synthetic DNA, enabling rapid, seamless assembly of even complex or repetitive constructs.
- Streamline screening and scale-up with benchtop protein expression systems, bringing variant libraries from concept to testing faster than ever.
- Cut development timelines and reduce risk with a fully integrated “Design–Build–Test” workflow, taking your enzyme projects from gene to functional insight with confidence.
Who should attend?
- Scientists and engineers in enzyme engineering, synthetic biology, and biocatalysis
- R&D leaders in pharma, biotech, and industrial biotech exploring rapid protein optimization
- Researchers working on DNA-binding proteins, transcription factors, or enzyme characterization
- Business development and innovation managers seeking strategic technology collaborations in the design–make–test space
Certificate of attendance
If you attend the live webinar, you will automatically receive a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
If you view the on-demand webinar, you can request a certificate of attendance by emailing editor@selectscience.net.
TechTalk: Advancing cell-free protein engineering workflows by translating enzyme variants into function
Monday, February 2 at 15:00 GMT | 16:00 CET | 10:00 EST | 7:00 PST
Traditional protein engineering is often constrained by iterative cycles, fragmented workflows, and limited reproducibility.
In this 20-minute TechTalk, Ribbon Bio will showcase a validated, fully cell-free design-build-test-learn (DBTL) workflow enabling one-shot optimization of a DNA-modifying enzyme. Based on a collaborative case study with Scala Biodesign and Nuclera, the session will illustrate how computational design, high-accuracy synthetic DNA, and rapid cell-free expression can be tightly integrated to deliver enzyme variants with superior biochemical performance.
Attendees will learn how linking expression metrics with functional readouts supports data-driven decisions, reduces development risk, and accelerates enzyme engineering for biocatalysis and synthetic biology.
Key learning objectives
- Understand how a fully cell-free, integrated design–build–test–learn (DBTL) workflow enables one-shot protein engineering without iterative optimization cycles.
- Learn how to translate computationally designed enzyme variants into reproducible expression and functional performance at application-relevant scale.
- Gain insight into linking expression metrics with biochemical and functional readouts to objectively assess and de-risk protein engineering campaigns.
- Evaluate how cross-platform integration (design, DNA synthesis, and expression) accelerates enzyme optimization for biocatalysis and synthetic biology applications.
Who should attend?
- Scientists and engineers working in enzyme engineering, synthetic biology, and biocatalysis
- R&D leaders working in pharma, biotech, and industrial biotech exploring rapid protein optimization
- Researchers working on DNA-binding proteins, transcription factors, or enzyme characterization
- Business development and innovation managers seeking strategic technology collaborations in the design–make–test space
Certificate of attendance
If you attend the live TechTalk, you will automatically receive a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
If you view the on-demand TechTalk, you can request a certificate of attendance by emailing editor@selectscience.net.
TechTalk details
- Cost: Free to attend
- Location: Online
- Duration: 20 minutes
Registration is required to secure your place. If you register but can’t attend live, you will receive a link to the on‑demand recording once it becomes available
Push the boundaries of what is possible with pristine synthetic DNA
Tuesday, July 15, 2025 at 15:00 BST / 16:00 CEST / 10:00 EDT / 07:00 PDT
Biopharma and life sciences demand DNA synthesis technologies that are highly accurate, flexible, and built for complexity. Join Dr. John Luckey and Divya Vijay Pratheek to explore how Ribbon Bio’s MiroSynth™ DNA delivers high-fidelity, long synthetic DNA through intelligent algorithms, enzymatic assembly, and automation. Designed for both linear and circular constructs, MiroSynth™ enables full traceability from sequence to molecule. This feature empowers researchers with confidence in every base.
Attendees will learn how Ribbon Bio is accelerating therapeutic development and will hear from Syngoi Technologies on how both companies are working together to make scalable synthetic DNA a reality for biopharma and life sciences.
Key learning objectives
- Discover how MiroSynth™ combines enzymatic assembly, automation, and intelligent algorithms for high-precision DNA synthesis.
- Learn how Ribbon supports both linear and circular DNA for advanced biopharma needs.
- See how end-to-end synthesis accelerates research and improves reliability.
- Understand how Ribbon has partnered with Syngoi Technologies to enable gram-scale DNA production for therapeutic development.
Who should attend?
- Heads of research and development
- Lab professionals
Certificate of attendance
If you attend the live webinar, you will automatically receive a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
If you view the on-demand webinar, you can request a certificate of attendance by emailing editor@selectscience.net.
