TSKgel SW Series Gel Filtration Columns for Proteins by Tosoh Bioscience

Manufacturer Tosoh Bioscience
3.3
/
5.0
  |  1 reviews
TSKgel SW-type columns for size exclusion/gel filtration analysis of antibodies and other proteins are silica-based. A hydrophilic diol-type bonded phase shields the silica surface from interacting with protein samples.  TSKgel SW-type columns contain more pore volume per unit column volume, which results in higher MW selectivity or better resolution. In addition, they show low adsorption and well-defined pore size distribution, which are requirements for high performance GFC of proteins. ... Read more


TSKgel SW Series Gel Filtration Columns for Proteins by Tosoh Bioscience product image
TSKgel SW Series Gel Filtration Columns for Proteins
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Average Rating: 3.3
1 Scientist has reviewed this product

4 out of 5
Ease of use
3 out of 5
After sales service
3 out of 5
Value for money


  • Status:

    Reviewer
  • Member since: 2019

  • Organization: Opocrin S.p.A



  • Ease of use
    4 out of 5
    After sales service
    3 out of 5
    Value for money
    3 out of 5
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Good quality, improvable batch to batch reproducibility.
Rating: 3.3

  • Application Area: High & low molecular weight heparin

"The columns are easy to use but take care when doing so. Loss of resolution on the low molecular weight region (column bench 3000 + 2000) occurs very quickly, especially in mobile phase sodium phosphate. Ammonium acetate buffered at pH 6 so they are more stable. It seems like some particular stationary phase batches are more stable and reproducible than others. These columns have never been cheap."

Review date: 07 Feb 2020 | TSKgel SW Series Gel Filtration Columns for Proteins

TSKgel SW-type columns for size exclusion/gel filtration analysis of antibodies and other proteins are silica-based. A hydrophilic diol-type bonded phase shields the silica surface from interacting with protein samples. 

TSKgel SW-type columns contain more pore volume per unit column volume, which results in higher MW selectivity or better resolution. In addition, they show low adsorption and well-defined pore size distribution, which are requirements for high performance GFC of proteins.

Various pore sizes are available in TSKgel SW, SWXL, SuperSW, UltraSW and UP-SW product lines.

  • TSKgel G3000SWXL is the working horse of the biopharmaceutical industry for aggregate analysis of therapeutic antibodies in QC. 
  • TSKgel UP-SW columns are optimized for use with UHPLC systems and allow a smooth transfer of standard methods from SWXL based HPLC analysis to UHPLC.
  • TSKgel SuperSW mAb columns are optimized for antibody separation.
  • TSKgel UltraSW Aggregate feature smaller particles and are optimized for analysis of higher aggregates.