Member since: 2019
Organization: Opocrin S.p.A
Good quality, improvable batch to batch reproducibility.
Application Area: High & low molecular weight heparin
"The columns are easy to use but take care when doing so. Loss of resolution on the low molecular weight region (column bench 3000 + 2000) occurs very quickly, especially in mobile phase sodium phosphate. Ammonium acetate buffered at pH 6 so they are more stable. It seems like some particular stationary phase batches are more stable and reproducible than others. These columns have never been cheap."
TSKgel SW-type columns for size exclusion/gel filtration analysis of antibodies and other proteins are silica-based. A hydrophilic diol-type bonded phase shields the silica surface from interacting with protein samples.
TSKgel SW-type columns contain more pore volume per unit column volume, which results in higher MW selectivity or better resolution. In addition, they show low adsorption and well-defined pore size distribution, which are requirements for high performance GFC of proteins.
Various pore sizes are available in TSKgel SW, SWXL, SuperSW, UltraSW and UP-SW product lines.