Thermo Scientific™ VolumeScope™ SEM by Thermo Fisher Scientific

Highest quality isotropic 3D data from large sample volumes. The Thermo Scientific™ VolumeScope™ scanning electron microscope (SEM) is a novel serial block-face imaging solution that enables excellent z-resolution from Multi-Energy Deconvolution SEM combined with the efficiency of in situ sectioning. The VolumeScope SEM unravels the complex 3D architecture of cells and tissues in their natural context, which is crucial for gaining an understanding of the structure-function correlation in biological systems. The VolumeScope SEM's automation and ease-of-use increase the productivity of operators of varying levels of expertise, allowing for acquisition of large sample volumes at isotropic resolution.

Key Benefits

• Truly isotropic 3D data from large volumes: Excellent z-resolution from Multi-Energy Deconvolution SEM combined with the efficiency of in situ sectioning.
• Highest contrast and resolution on all samples: Highest contrast and optimal SNR with in-lens and in-column detectors for HiVac, as well as dedicated detectors for optimal resolution in LoVac.
• Simple switch between normal SEM use and serial block face imaging: Compact, stage-mounted microtome allowing easy exchange.
• Instant productivity for all operators: High degree of automation and design for ease-of-use adding to operator efficiency and inspiring greater experimentation.
• Increased efficiency and accuracy thanks to workflow solutions: Fast identification of regions of interest by CLEM approaches and large volume coverage with automated multi-tile set runs.