Status:
ReviewerMember since: 2017
Organization: SUNY Buffalo
Great results. Very consistent system.
Application Area: Proteomics
"Simple to use VERY flexible system. Can do small molecules as well as proteomics"
Status:
ReviewerMember since: 2018
Organization: Umeå University
Good quality and reproductivity.
Application Area:Proteomics
"Nice operation experience and easy hand-on practice."
Status:
ReviewerMember since: 2018
Organization: Umeå University
Super MS device and can’t obtain good results without it!
Application Area:Phosphoproteomic analysis
"The instrumental effectiveness has been shown quite well during the past years’ practical application and test work. The satisfactory analytical results’ reproducibility has also been achieved most of the time. The instrument is relatively easy to control even for beginners and it’s a good choice in terms of performance/cost ratio and maintenance service as well."
Status:
ReviewerMember since: 2020
Organization: Fraunhofer Institute (IME)
Application Area:Pesticides, food, and environmental analysis
"Long life, reliable and stable instrument for qualification (MSn) and quantification."
Status:
Advanced ReviewerMember since: 2019
Organization: Case Western Reserve University
Perfect MS instrument for protein characterization.
Application Area:Hydrogen deuterium exchange and hydroxyl radical footprinting
"This is my first MS instrument and I really liked it. This instrument is so robust and easy to work with. I have used it for hydrogen/deuterium exchange and hydroxyl radical foot-printing experiments. It gives reprodicible results with good signal and minimum sample requirement."
Status:
Advanced ReviewerMember since: 2019
Organization: Access Medical Laboratories
Exceptional.
Application Area:Small molecules
"Exceptional performance, exceptional training programs by Thermo Scientific."
Status:
ReviewerMember since: 2019
Organization: The University Of Kansas
Relatively easy to interface with home build CE.
Application Area:Mass spectrometric analysis of peptides
"We use Thermo Fisher LTQ XL system for analysis of small peptides. The MS is bit old but still works well."
Status:
ReviewerMember since: 2019
Organization: Texas Tech University
Powerful instrument.
Application Area:Analysis of biological macromolecules such as proteins and glycans.
"It is one of the powerful mass spctrometers and met most of our requirment for research. The after sale services is also professional and efficient."
Status:
ReviewerMember since: 2019
Organization: University Of Naples
My favorite instrument in lab.
Application Area:Proteomics
"The instrument enables high quality results with high sensitivity and accuracy in mass spectrometry-based identification of proteins in complex mixtures."
Status:
Advanced ReviewerMember since: 2015
Organization: Xen Biofluidx
A must-have lab instrument in processes involving high yield purification.
Application Area:Intermediate and final product purification
"The equipment is absolutely instrumental in our lab processes in consistently providing good yield and purity level."
Status:
Advanced ReviewerMember since: 2015
Organization: Xen Biofluidx
A ubiquitous tool like the pH meter and balance
Application Area:Purification of intermediates and final products
"A great and indispensable lab tool that confers great and consistent yield and high purity."
Status:
Advanced ReviewerMember since: 2015
Organization: Xen Biofluidx
I cannot live without this lab tool. It's like a pH meter.
Application Area:Purification of intermediates and final products.
"Great yield and purity of intermediates and final products."
Status:
Advanced ReviewerMember since: 2015
Organization: Xen Biofluidx
An indispensable lab tool.
Application Area:Purification
"Effective tool to use to purify intermediates and final products with good yield and level of purity."
Status:
Advanced ReviewerMember since: 2015
Organization: Xen Biofluidx
Very Reliable and Effective Means of Purification.
Application Area:Product/intermediate purification
"Good yield with exceedingly high desired product purity."
Status:
ReviewerMember since: 2013
Organization: Mallinckrodt Pharmaceuticals
Excellent instrument for structure elucidation.
Application Area:Unknown Identification in pharmaceuticals (impurities, degradants, contaminants)
"This instrument is very easy to use and gives incredible mass accuracy, which makes obtaining formulae for both precursor and product (MSn) ions fairly easy. The MSn capability does add the ability to acquire a great deal of data to help in the structure elucidation, although considerable expertise is needed to interpret the data. The sensitivity of the instrument is very good in general, although it may be a little less than some other instruments on the very small molecule end. I would highly recommend this instrument!"
Status:
ReviewerMember since: 2016
Organization: Imperial College London
Great for quantitative proteomics good workhorse instrument good software
Application Area:proteomics
"Use this instrument to identify and quantitate protein from complex samples, also used it to identify phosphorylation sites in cancer cell lines. Resolution and accuracy make it suitable of this kind of work! "
Status:
Expert ReviewerMember since: 2016
Organization: Eastern Virginia Medical School
Quality instrument
Application Area:Proteomic analysis of biological fluids
"We use this MS for the majority of our proteomics work. It has been a workhorse machine."
Status:
ReviewerMember since: 2015
Organization: University of Oklahoma
I really enjoy using this instrument
"I really enjoy using this instrument, and even though we bought it from Thermo as a refurbished instrument, it has been working pretty well for the past 5 years."
Status:
ReviewerMember since: 2013
Organization: Dr.Reddys Ltd
Application Area:Biopharmaceuticals
"It is one of the best iontrap instrument I have ever used. It delivers the best MS and MS/MS result for protein identification and characterization. The sensitivity and mass accuracy is very good. it makes impurity characterization at the ease, very rugged instrument too. It is best suitable for biopharmaceutical applications."
Status:
ReviewerMember since: 2006
Organization: University of Missouri
Application Area:Proteomics
"Generates lots of good data with relatively modest file sizes. User interface is easy to use. Accurate mass is great."
The Thermo Scientific LTQ Orbitrap XL hybrid FTMS (Fourier Transform Mass Spectrometer) supports a wide range of applications from routine compound identification to the most challenging analysis of low level components in complex mixtures. The LTQ Orbitrap XL is based on the fast and highly sensitive Thermo Scientific LTQ XL linear ion trap and the patented Orbitrap* technology. The LTQ Orbitrap XL features a new HCD collision cell for ultimate flexibility in fragmentation experiments for advanced proteomics and small molecule research.
Key features of the Thermo Orbitrap XL include:
Outstanding Mass Accuracy, Resolution, Dynamic Range and Sensitivity
• Featuring the new HCD collision cell for ultimate flexibility in fragmentation experiments for advanced proteomics and small molecule research
• Superior mass accuracy for lower false positive rates (FPRs)
• Parallel acquisition mode for optimized productivity
From Protein ID to Biomarker Discovery with the Thermo LTQ Orbitrap
• Excellent sensitivity and fragmentation efficiency
• Reliable identification and quantitation in one experiment
High quality data from the LTQ Orbitrap XL for reliable de novo sequencing
• Superior mass accuracy and high resolution leading to confident de novo sequencing results
• Multiple collision modes (CID and HCD) for comprehensive structural information