Fetal Bovine Serum for Cell Culture (Tetracycline-Free)
High-quality Tet System Approved Fetal Bovine Serum for cell culture has been functionally tested* to ensure that it permits the full range of tetracycline-regulated induction with well-characterized Tet cell lines. As the exclusive licensed distributor of tetracycline-controlled gene expression systems, only Clontech is certified to offer FBS that can ensure optimum induction with all tetracycline inducible gene expression systems. Other commercial cell culture serum products may contain tetracycline-derived contaminants which can dramatically affect the inducible regulation of Tet Systems.
Because Clontech's Tet-On and Tet-Off Systems are extremely sensitive, even “antibiotic-free” fetal bovine serum that has no negative effect on cell growth may still exhibit enough activity to alter Tet-regulated gene expression. You can be confident that Tet System Approved FBS will not adversely affect Tet-On or Tet-Off experiments.
*Testing for the presence of tetracyclines in fetal or calf serum is not equivalent to the highly sensitive functional testing that is performed on Clontech Tet System Approved FBS.