StemSpan™ Megakaryocyte Expansion Supplement (100X)
Serum-free culture supplement for expansion of human megakaryocytes
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StemSpan™ Megakaryocyte Expansion Supplement (100X) (formerly known as CC220) contains a combination of recombinant human cytokines (SCF, IL-6, IL-9 and TPO) formulated to selectively promote the expansion and differentiation of human megakaryocyte progenitor cells from CD34+ cells isolated from human cord blood (CB) or bone marrow samples. StemSpan™ Megakaryocyte Expansion Supplement is intended for use in combination with StemSpan™ SFEM, SFEM II and -ACF serum-free expansion media, or any other media for culturing human hematopoietic cells.
When added to serum-free medium, StemSpan™ Megakaryocyte Expansion Supplement typically promotes the production of hundreds of megakaryocytes per input CD34+ cell in 14-day liquid cultures initiated with CD34+ human CB cells. See data tab for more details.
This product is recommended for:
- Research into the regulation of megakaryocytopoiesis
- Development of procedures to expand megakaryocytes and platelets in culture
